The term phytomedicine was coined by French physician Henri Leclerc in 1913. Till recently phytomedicine has remained in the background. But due to emerging challenges to the conventional pharmaceutical industry (cost effectiveness and potency of the drugs), phytomedicine has made a dramatic comeback. Phytomedicine has witnessed several changes and several new concepts have been introduced. Phytomedicine, although, a separate discipline, is strongly linked to Phytotherapy and Phytopharmacology.As the title suggests the book is an attempt to bridge the gap between fundamental and emerging concepts in this field of medicine. The book has been divided into two parts. Part A deals with core issues of the phyto-pharmaceutical drug industry. The book begins with an introductory chapter dealing with basic definitions with phytomedicine. Chapters 2-5 narrate emerging subjects such as Phytopharmacovigilance, Phytopharmacoeconomics, Phytopharmacoepidemiology and Phytopharmacogenomics. Chapter 6 discusses ethical issues in phytomedicine. Chapter 7 covers recent advances in drug delivery systems in phytomedicine whereas Chapter 8 is about application of nanotechnology in the field of phytomedicine. The further chapters cover metabolomics, regulatory and legal aspects of the phyto-pharmaceutical drug industry. The chapter on herbal bioavailability enhancing agents is the salient feature of Part-A. Part B is related to applied research in the field of phytomedicine. Experimental findings on phyto-bioactive agents such as withanolides, steroidal alkaloids, phytosteroids and phytocannabinoids have been elaborated.Nine annexures related to herbal drug registration are included.
Dr. Amritpal Singh completed his Bachelor's and Master's degree in Ayurveda (a system of traditional Indian medicine) from Guru Nanak Dev University, Amritsar, India and B.R. Ambedkar Bihar University, Muzaffarpur, India respectively. He also holds an MSc degree in Medicinal Plants from Nagaland Open University, Nagaland and has done specialized courses in phytochemical techniques, medicinal botany and ethnopharmacology.
He started his career as an Ayurvedic Medical Officer and later became an herbal consultant. He subsequently joined as external faculty at the National Institute of Pharmaceutical Education and Research, Mohali, Punjab and became a Senior Lecturer in Lovely Professional University, and at Dhanwantari Ayurvedic College, Chandigarh. Presently he is consultant to several national and international organizations. He has authored more than 20 books and presented more than 100 papers in Indian and international seminars and conferences. His work on herbal medicinal plants has earned him recognition.
PART-A: INDUSTRIAL ASPECTS OF PHYTOMEDICINE
Introduction to Phytomedicine
Ethics in Phytomedicine
Metabolomics and Phytomedicine
Clinical Research in Ayurveda
Excepients for Phytomedicine
Certifications for Phytodrug Industry
Acts Related to Banned or Restricted Phyto Ingredients
Comfrey Based Herbal Products
PART-B: BIOACTIVES FROM PHYTOMEDICINE
Phytosteroids and Related Compounds
Botany of Phytosteroids Containing Medicinal Plants
Pharmacology of ¿-Sitosterol and Other Sterols
Pharmacology of Disogenin and Related Compounds
Botany of Withanolides Containing Medicinal Plants
Pharmacology of Withaferin A
Pharmacology of Withanolide A
Pharmacology of Withanone
Pharmacology of Withanolide D
Annexures (1-9) Related to Herbal Drug Registration
Acronyms and Abbreviations