Epigenetics and Public Policy: The Tangled Web of Science and Politics

Praeger (Verlag)
  • erschienen am 19. April 2018
  • |
  • 365 Seiten
E-Book | ePUB mit Adobe DRM | Systemvoraussetzungen
978-1-4408-4470-6 (ISBN)
Epigenetics--the study of internal and environmental factors that affect how genes are turned on or off and how cells read those genes--is a rapidly emerging science akin to genetics that introduces a number of novel and unexpected biological explanations of human origins and development. It also poses fundamental challenges to many of the assumptions of the prevailing science of genetics. When science changes, how does public policy respond? This book comprehensively considers the political implications of the emerging science of epigenetics in specific policy domains, addressing the intersections of epigenetics with cancer, obesity, the environment, and the law. Author Shea K. Robison carefully navigates the messy history of genetics and epigenetics in order to explore what changes in public policy might come in the age of a new scientific frontier. Readers will understand how new findings in epigenetic research and increased acceptance of epigenetic science may lead to paradigm shifts in cancer prevention and treatment, significantly different policy solutions for combating obesity, and revised statutes of limitations and laws regarding civil and corporate liability and wrongful life.
  • Englisch
  • Santa Barbara
  • |
  • USA
978-1-4408-4470-6 (9781440844706)
1-4408-4470-4 (1440844704)
weitere Ausgaben werden ermittelt
  • Cover
  • Title
  • Copyright
  • Contents
  • Acknowledgments
  • Introduction: Epigenetics and Public Policy: The Tip of the Iceberg
  • The What of Epigenetics
  • The When of Epigenetics
  • The Why of Epigenetics and Politics: The Epipolitics Model
  • Part 1: The Science of Epigenetics
  • Chapter 1: Epigenetics 101
  • Genetics
  • Genes and Evolution
  • How Epigenetics Works
  • Methylation
  • Chromatin Remodeling
  • RNA-Mediated Inheritance
  • Conclusion
  • Environmental Responsiveness
  • Epigenetic Inheritance
  • Chapter 2: Epigenetics and Inheritance: Past, Present, and Future
  • A Brief History of Inheritance (and Why It Is Still Important Today)
  • Inheritance before Darwin
  • Inheritance after Darwin (and Mendel)
  • Inheritance, Politics, and Epigenetics
  • What Is Epigenetic Inheritance?
  • Cell-to-Cell Epigenetic Inheritance
  • Organism-to-Organism Epigenetic Inheritance
  • Soma-Germ Line Epigenetic Inheritance
  • Intergenerational Epigenetic Inheritance
  • Transgenerational Epigenetic Inheritance
  • Epigenetic Inheritance in Humans
  • Conclusion
  • Part 2: The Political History of Epigenetics
  • Chapter 3: Epigenetics, Lamarck, and Politics
  • "Epigenetics" through History
  • Epigenetics and the Left
  • Epigenetics and the Right
  • Epigenetics, Politics, and Narratives
  • Jean-Baptiste Lamarck: Evolution (and "Epigenetics") before Darwin
  • The Unfortunate Legacy of Lamarck
  • Lamarck's Actual Lamarckism (or How Contemporary Epigenetics Is Not Lamarckian)
  • Darwin, Lamarck, and "Epigenetics"
  • Judging Lamarck
  • Weismann and Lamarck
  • Conclusion
  • Chapter 4: The Evolution of Evolution
  • Biology and Society in the 1800s
  • Science, Society, and Ideology
  • Geology, Biology, and Society
  • Geology and Religion
  • Geology and Biology
  • Biology and Politics
  • Lamarck to Darwin
  • Chapter 5: Lamarck to Darwin
  • Epigenetics: A Revolution from Within
  • Lamarckism and Darwinism: Separated at Birth?
  • Two Diverging Roads
  • Charles Lyell: The "Missing Link" between Lamarck and Darwin
  • Lyell and Lamarck
  • Lyell and Darwin
  • The Biology of Contentment and Discontent
  • Order as the Natural Order
  • The Other Side of Evolution
  • Alfred Russel Wallace: Socialism, Ideology, and Evolution
  • Conclusion
  • Chapter 6: Ideology and Biology at the Turn of the Century
  • The Evolution of Evolution and Genetics
  • The Politics of the "Eclipse" of Darwinism
  • Eugenics, Genetics, and "Epigenetics"
  • The "Epigenetics" of Neo-Lamarckism
  • Genetics and the Progressive Movement in America
  • Science, Eugenics, and the New State
  • Chapter 7: C. H. Waddington and the Genesis of Epigenetics
  • The Beginning of Actual Epigenetics
  • The Genesis of Waddington the Epigeneticist
  • Waddington, the Embryologist
  • Epigenetics, Politics, and Science
  • A Tale of Two Fields
  • Drifting or Running Apart?
  • The Failure of Rapprochement
  • The Birth of Epigenetics
  • Why "Epigenetics"?
  • Epigenetics and the Healing of Modern Science
  • Chapter 8: Epigenetics and the Dustbin of History
  • Epigenetics and Socialism?
  • Waddington and the Theoretical Biology Club
  • J. B. S. Haldane
  • J. D. Bernal
  • Science and Ideology
  • "Epigenetics" and the Cold War in the USSR
  • Evolution and Ideology in Russia and the USSR
  • Genetics in the USSR
  • Lamarck, Lysenko, and "Epigenetics" in the USSR
  • Lamarckism and Political Ideology
  • "Epigenetics" and the Cold War in the United States
  • Ralph Spitzer
  • L. C. Dunn
  • Epigenetics and Hegemony
  • Underneath the Science
  • Geography, War, and Genetics
  • Follow the Money
  • Conclusion
  • Part 3: Epigenetics in Public Policy
  • Chapter 9: Epigenetics and Obesity: Cause and Responsibility
  • The Science of Epigenetics and Obesity
  • Epigenetics and Obesity
  • Prader-Willi Syndrome
  • Epigenetics, Early Development, and Later Obesity
  • Epigenetics and the Expansion of the Developmental Environment
  • The Narratives of Epigenetics and Obesity Policy Obesity in History and Society
  • Obesity as Focus of Public Policy
  • Obesity Narratives
  • Public Health Policy and Ideology as Causal Narrative
  • Obesity Policy and Ideology
  • Chapter 10: A Short Political History of Cancer
  • Cancer and the Politics of Science and Public Policy
  • Cancer and the Language of Military Mobilization
  • Cancer and the Reorganization of Government
  • Early Cancer Legislation
  • Early Public Cancer Control Efforts
  • The American Society for the Control of Cancer
  • Cancer Control and the Changing Role of Government
  • Cancer Control and Eugenics
  • Mary Lasker: Cancer, Birth Control, and the Government
  • Chapter 11: Contemporary Epigenetics and the Causes of Cancer
  • Cancer, Genes, and Epigenetics
  • Cancer, Epigenetics, Inheritance, and Politics
  • Epigenetics and Cancer around the Body and around the World
  • When Random Is Not Random
  • Cancer, "Bad Luck," and Politics
  • The Response to Bad Luck
  • Chapter 12: Shifting Foundations: Cancer, Genetics, and Epigenetics
  • Epigenetics and Bad Luck
  • Epigenetics and Cancer: From Sequences to Contexts
  • Epigenetics, Mutations, and Cancers
  • Epigenetics, Stem Cells, and Cancer beyond Mutations
  • Out of the Bottle and into the China Shop
  • Conclusion: The Tangled Web of Science and Politics
  • The Epipolitics Model in History
  • Radicalism in the 1800s
  • The Progressive Era
  • The Cold War
  • Epipolitics and Epigenetics Today
  • Epigenetics and Public Policy
  • Epigenetics and Ideology in Public Policy
  • Epigenetics, Policy, and the Epipolitics Model
  • Notes
  • Introduction
  • Chapter One
  • Chapter Two
  • Chapter Three
  • Chapter Four
  • Chapter Five
  • Chapter Six
  • Chapter Seven
  • Chapter Eight
  • Chapter Nine
  • Chapter Ten
  • Chapter Eleven
  • Chapter Twelve
  • Conclusion
  • Index
  • About the Author

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