Stem Cells and Signaling Pathways provides mechanistic insights into the role of stem cells to combat the COVID-19 outbreak and other pathologies where a cytokine storm is the cause of concern for e.g., radiation exposure, multiple organ failure and sepsis. The advent of SARS-CoV-2 resulted in a global pandemic, putting individuals with other comorbidities at a higher risk of infection. The whole world witnessed a massive shortage of medical and other essential supplies needed to combat the virus. That said, stem cell therapy has emerged as a potential treatment for viral diseases, including but not limited to COVID-19.
Interestingly, the clinical trials in the patients having COVID-19 complications depicted faster recovery in patients post mesenchymal stem cells therapy owing to the decreased cytokines levels, anti-viral effects and regeneration of the infected tissue.
- Provides a compilation of chapters dedicated to the study of the field with respect to properties of stem cells and their signaling pathways. It also provides detailed information on signaling pathways associated with stem cells
- Provides a detailed and updated view of stem cell biology
- Covers a wide range of areas within basic and translational research appropriate for scientists and clinicians engaged in studying the treatments for diseases from interdisciplinary perspectives
- Highlights the use of different models for stem cell research, significance of stem cell signaling in drug discovery
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-443-18801-5 (9780443188015)
Schweitzer Klassifikation
1. Regulation of mesenchymal stem cell differentiation by key cell signaling pathways2. Stem signaling molecules and pathways: Implications in the regulation of fate and proliferation3. The role of Yamanaka factors in induced pluripotent stem cells and embryonic stem cells signaling 4. Purinergic signaling in stem cell growth5. Cutaneous Homeostasis: A Balancing Cross-Talk Between Epidermal Stem Cell Pool and Regulatory Pathways6. Role of Stem Cells in Cardiac Bioengineering7. Stem Cell Signaling Molecules and Pathways in Liver Regeneration8. Role of stem cells in osteoblastic miRNA and bone tissue regeneration9. Stem cells and Signaling Pathways in Human Reproductive System10. Hormonal Impacts on Stem Cell Lineages and Related Signaling Pathways11. Unravelling the crosstalk of Hedgehog with Wnt, Notch, and TGF-ß signaling pathways12. Stem cell aging: Role of signaling pathways and microRNAs13. Slowdown of ageing and neurodegenerative diseases by extremolytes14. Stem cells and therapy; cancer stem cells and targeted therapy with DNA repair inhibitors15. The potential role of stem cells in multiple sclerosis therapies16. Stem cells signaling pathways and surface receptors: implications for Multiple Sclerosis treatment17. Mechanistic role of stem cells in the pathogenesis and treatment of oral diseases: current insights and future directions18. Stem cell-based approach in treatment of periodontitis19. Role of probiotics in modulation of stem cell progeny in human gastrointestinal disorders20. Implications of stem cell-associated signals in pathogenesis of lipid disorders21. Stem cell's potential role in the treatment of diabetes mellitus22. Mesenchymal Stem Cells in Chronic Kidney Disease and Therapeutic Signaling Pathways23. Current Advances and Challenges in Stem Cell-Based Therapy for Chronic Kidney Disease24. Stem cell therapeutic approaches and signaling pathways in rheumatoid arthritis and osteoarthritis25. Potential role of stem cells in pathogenesis of endometriosis.26. Potential role of traditional medicine in stem cell research
