Advances in Virus Research

 
 
Elsevier (Verlag)
  • 1. Auflage
  • |
  • erschienen am 30. April 2020
  • |
  • 178 Seiten
 
E-Book | ePUB mit Adobe DRM | Systemvoraussetzungen
978-0-12-820755-0 (ISBN)
 

Advances in Virus Research, Volume 106, the latest in the series, contains new, informative updates on the topic. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.

  • Contains contributions from leading authorities in the field of virology
  • Informs and updates on all the latest developments in the field
  • Englisch
  • San Diego
  • |
  • USA
  • 16,21 MB
978-0-12-820755-0 (9780128207550)
weitere Ausgaben werden ermittelt
  • Intro
  • Advances in Virus Research
  • Copyright
  • Contents
  • Contributors
  • Chapter One: Influenza A virus uncoating
  • 1. Fundamentals of IAV entry
  • 2. Multistep IAV uncoating in endosomes
  • 3. IAV fusion and cytosolic uncoating
  • 4. Histone deacetylases (HDACs) in IAV entry: What sets HDAC6 apart from other HDACs
  • 5. HDAC6 regulates cellular stress granules, aggresomes and phase separation
  • 6. HDAC6 uncoats IAV via ubiquitin chains and the aggresome pathway
  • 7. Karyopherin-ß2 (transportin-1/TNPO1): A cellular condensate surveillance factor
  • 8. The link between IAV uncoating and management of cellular condensates
  • 9. vRNP nuclear import
  • 10. How IAV prevents uncoating during assembly
  • 11. Kapß2 is a universal uncoating factor
  • 12. Concluding remarks
  • Acknowledgment
  • References
  • Chapter Two: Structural and cellular biology of adeno-associated virus attachment and entry
  • 1. Introduction
  • 2. AAV attachment factors and receptors
  • 2.1. Glycan attachment factors
  • 2.1.1. Heparan sulfate
  • 2.1.2. Sialic acid
  • 2.1.3. N-linked galactose
  • 2.2. Proteinaceous co-receptors
  • 2.3. The AAV multi-serotype receptor
  • 2.4. Structural interactions between AAV and AAVR
  • 3. Model for AAV cellular entry and trafficking
  • 3.1. Attachment and endocytosis
  • 3.2. Trafficking to the Golgi apparatus
  • 3.3. Escape to the cytoplasm and nuclear import
  • 4. Outlook and translational impacts
  • 4.1. Role of attachment factors and receptors in vivo
  • 4.2. AAV in the lung
  • 4.3. AAV in the brain
  • 4.4. Retargeting AAV in vivo
  • 5. Concluding remarks
  • References
  • Chapter Three: From foes to friends: Viral infections expand the limits of host phenotypic plasticity
  • 1. Introduction
  • 1.1. Phenotypic plasticity, reaction norms and niche breadth
  • 1.2. Viruses as non-pathogenic symbionts
  • 1.3. Plant responses to abiotic environmental stresses
  • 2. Virus-induced tolerance to abiotic stresses
  • 2.1. Water stress
  • 2.1.1. Drought
  • 2.1.2. Flood
  • 2.2. Extreme temperatures
  • 2.2.1. High temperatures
  • 2.2.2. Low temperatures
  • 2.3. Excess of light irradiation
  • 2.4. Oxidative stress
  • 3. Mechanisms of virus-induced tolerance
  • 3.1. Plant phenotypic and physiological changes in response to infection
  • 3.2. Plants short-term adaptation to stress by epigenetic changes
  • 3.3. Viral population dynamics and virus adaptation to abiotic stresses
  • 3.4. The environment as a key factor in host-virus interaction
  • 4. Concluding remarks
  • Acknowledgments
  • References
  • Further reading
  • Chapter Four: Exploration of the interactions between mycoviruses and Fusarium graminearum
  • 1. Introduction
  • 2. Omics approaches for understanding the Fusarium graminearum-mycovirus interactions
  • 3. Identification of Fusarium host factors affecting accumulation and/or transmission of FgVs
  • 4. RNAi defense responses of Fusarium graminearum against FgVs
  • 5. Functional characterization of genes encoded by FgVs
  • 6. Conclusions and perspectives
  • Acknowledgments
  • References
  • Chapter Five: Implications of mixed viral infections on plant disease ecology and evolution
  • 1. Introduction
  • 2. Within-host microbe interactions
  • 2.1. Virus-virus interactions
  • 2.2. Virus and interactions with other microbes
  • 3. Influence of mixed infections on the maintenance of viral genetic diversity
  • 4. Mixed infections shaping the spatial distribution and temporal dynamics of plant virus populations
  • 4.1. Mixed infections at the host-scale
  • 4.2. Mixed infections at the field-scale
  • 5. Concluding remarks
  • Acknowledgments
  • Conflict of interest
  • References

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