The Neuroscience of Parkinson's Disease (two volume set) provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. The book also fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson's disease-from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.
- Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease
- Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction
- Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
- Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations
- Serves as a "one-stop" source for everything you need to know about Parkinson's disease
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
ISBN-13
978-0-12-815959-0 (9780128159590)
Schweitzer Klassifikation
Section 1 Parkinson's Disease: Introductory Chapters1. A Short History of Parkinson's Disease - from early 19th century and afterwards - an overview2. Living with Parkinson's disease - from financial to emotional3. The epidemiology of Parkinson's disease - an overview4. Clinical Features of Parkinson's disease - an overview5. The natural history of Parkinson's disease - an overview6. The prognosis of Parkinson's disease - an overview7. The neurobiology of Parkinson's disease - an overview8. The pathophysiology of Parkinson's disease - an overview9. Molecular and cellular mechanisms associated with Parkinson's disease - synuclein, amyloid protein, oligomers and beyond10. Quality of life in Parkinson's disease11. Gait in untreated Parkinson's disease12. Levodopa-induced dyskinesias13. Tremor in Parkinson's disease14. The impact of Parkinson's disease on the family and careers
Section 2 Biomarkers and Diagnosis15. Tissue biopsies as biomarkers in Parkinson's disease16. Spinal fluid for biomarker discovery in Parkinson's disease17. Clinical biomarkers in prodromal Parkinson's disease18. The diagnosis of Parkinson's disease19. Proteomics in Parkinson's disease20. MicroRNAs as biomarkers in Parkinson's diseases21. Phenotyping in Parkinson's disease22. Diagnosis of speech disorders in Parkinson's disease23. Identifying dementia in Parkinson's disease24. Diagnosis of sleep disturbances in Parkinson's disease25. Diagnosis of Parkinson's disease using magnetic resonance imaging26. Use of ultrasound as a diagnostic tool in Parkinson's disease27. Use of single-photon emission computerized tomography (SPECT) as a diagnostic tool in Parkinson's disease28. Use of positron emission tomography (PET) as a diagnostic tool in Parkinson's disease
Section 3 Pharmacological Treatments for Parkinson's Disease29. Dopamine Agonists and Parkinson's disease - an overview30. Management with Levodopa in Parkinson's disease31. Management with ripinirole in Parkinson's disease32. Management with pramipexole in Parkinson's disease33. Management with rotigotine in Parkinson's disease34. Management with apomorphine in Parkinson's disease35. Management with MAO-B Inhibitors in Parkinson's disease36. Management with COMT inhibitors in Parkinson's disease37. Management with anticholinergics in Parkinson's disease38. Management with amantadine in Parkinson's disease
Section 4 Novel and Non-Pharmacological Therapies For Parkinson's Disease39. Treatment with chelator in Parkinson's disease40. Treatment with deep brain stimulation in Parkinson's disease41. Olive leaf extract usage as an antioxidant and applications to Parkinson's disease42. Treatment with Vitamin D for Parkinson's disease43. Chemogenetics and applications for Parkinson's disease44. Flavonoids and naringin usage in Parkinson's disease45. Stem cells and applications to Parkinson's disease46. Treatment with cannabis for Parkinson's disease47. Treating sleep problems in Parkinson's disease48. Perioperative treatments of Parkinson's disease49. Exercise and Parkinson's disease50. Molecular aspects: CB2 receptors and neuroprotection in Parkinson's disease
