This book provides a concise overview of emerging technologies in the field of modern neuroimaging. Fundamental principles of the main imaging modalities are described as well as advanced imaging techniqes including diffusion weighted imaging, perfusion imaging, arterial spin labeling, diffusion tensor imaging, intravoxel incoherent motion, MR spectroscopy, functional MRI, and artificial intelligence. The physical concepts underlying each imaging technique are carefully and clearly explained in a way suited to a medical audience without prior technical knowledge. In addition, the clinical applications of the various techniques are described with the aid of illustrative clinical examples. Helpful background information is also presented on the core principles of MRI and the evolution of neuroimaging, and important references to current medical research are highlighted. The book will meet the needs of a range of non-technological professionals with an interest in advanced neuroimaging, including radiology researchers and clinicians in the fields of neurology, neurosurgery, and psychiatry.
Manoj Mannil is Senior Consultant for Diagnostic Neuroradiology at the University Hospital of Münster, Germany. After his medical education at the Georg-August University Göttingen, Germany, he obtained his doctorate (Dr. med.) at the Max Planck Institute for Experimental Medicine in Germany. He completed a Master of Science in Advanced Neuroimaging from the University College London, UK. His residency in General Radiology was performed at the City Hospital Triemli and the University Hospital of Zurich in Switzerland. He completed his fellowship training in Neuroradiology at the University Hospital in Zurich, Switzerland. His teaching appointments in Germany and Switzerland, focus on all aspects of clinical Radiology. His research work focuses on advanced neuroimaging techniques, with special interest in artificial intelligence and Radiomics.
Sebastian Winklhofer is a neuroradiologist at the Department of Neuroradiology at the University Hospital in Zurich, Switzerland. He received his medical degree from the RWTH Aachen, Germany (2008) and completed his residency in radiology and his fellowship in neuroradiology at the University Hospital Zurich. He spent one year at the University of California, San Francisco for a research fellowship focused on advanced techniques in computed tomography. Next to his doctoral thesis in radiology, he received the "Venia Legendi" (Privatdozent) for radiology from the University of Zürich. His clinical work is focusing on head and neck imaging and on oncological and vascular diseases of the CNS. Ongoing research projects include the application of new imaging techniques such as dual-energy CT or intravoxel incoherent motion imaging. Among other awards, Dr. Winklhofer received the RSNA Trainee Research Prize in 2012 and the Peter Huber Prize 2017 of the Swiss Society of Neuroradiology.
Introduction.- Ultrasound in Neuroimaging.- X-Ray.- Basics of Computed Tomography.- CT Angiography.- CT Perfusion.- Flat Panel CT/ Cone Beam CT.- Dual Energy CT.- Photon counting CT.- Basics of Magnetic Resonance Imaging.- MR Angiography.- Perfusion Techniques.- Susceptibility Weighted Imaging.- Diffusion weighted Imaging (DWI).- Diffusion tensor imaging.- Diffusion kurtosis imaging Technical background and clinical applications.- IVIM Technical background and clinical applications .- MR Spectroscopy.- MTR .- Functional MRI .- PET in Neuroimaging.- EEG.- Radiomics - Outlook into the future.