Gut-Brain Axis

Dietary, Probiotic, and Prebiotic Interventions on the Microbiota
 
 
Academic Press
  • 1. Auflage
  • |
  • erschienen am 13. Mai 2016
  • |
  • 508 Seiten
 
E-Book | ePUB mit Adobe DRM | Systemvoraussetzungen
E-Book | PDF mit Adobe DRM | Systemvoraussetzungen
978-0-12-802544-4 (ISBN)
 

The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders.


  • Focuses on specific areas in which the microbiota has been implicated in gut-brain communication
  • Examines common mechanisms and pathways by which the microbiota may influence brain and behavior
  • Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior
  • Englisch
  • San Diego
  • |
  • USA
Elsevier Science
  • 6,13 MB
978-0-12-802544-4 (9780128025444)
0128025441 (0128025441)
weitere Ausgaben werden ermittelt
  • Intro
  • Title page
  • Table of Contents
  • Copyright
  • List of Contributors
  • Preface
  • Chapter 1. Regulatory Considerations for the Use and Marketing of Probiotics and Functional Foods
  • Chapter 4. Value of Microbial Genome Sequencing for Probiotic Strain Identification and Characterization: Promises and Pitfalls
  • Chapter 2. Targeting the Microbiota: Considerations for Developing Probiotics as Functional Foods
  • Chapter 5. Probiotics as Curators of a Healthy Gut Microbiota: Delivering the Solution
  • Chapter 7. Germ-Free Animals: A Key Tool in Unraveling How the Microbiota Affects the Brain and Behavior
  • Chapter 6. Microbial Endocrinology: Context and Considerations for Probiotic Selection
  • Chapter 3. Perspectives on Microbiome Manipulation in People of Developing Countries
  • Chapter 8. Global and Epidemiological Perspectives on Diet and Mood
  • Chapter 10. The Microbiome in Aging: Impact on Health and Wellbeing
  • Chapter 9. Importance of the Microbiota in Early Life and Influence on Future Health
  • Chapter 11. Long-Term Implications of Antibiotic Use on Gut Health and Microbiota in Populations Including Patients With Cystic Fibrosis
  • Chapter 12. Correlating the Gut Microbiome to Health and Disease
  • Chapter 13. The Hypothalamic-Pituitary-Adrenal Axis and Gut Microbiota: A Target for Dietary Intervention?
  • Chapter 14. A Role for the Microbiota in Neurodevelopmental Disorders
  • Chapter 16. The Influence of Diet and the Gut Microbiota in Schizophrenia
  • Chapter 15. Altering the Gut Microbiome for Cognitive Benefit?
  • Chapter 17. Alcohol-Dependence and the Microbiota-Gut-Brain Axis
  • Chapter 19. Influence of the Microbiota on the Development and Function of the "Second Brain"-The Enteric Nervous System
  • Chapter 18. Gut Microbiota and Metabolism
  • Chapter 20. Dietary Interventions and Irritable Bowel Syndrome
  • Chapter 21. The Role of the Microbiota and Potential for Dietary Intervention in Chronic Fatigue Syndrome
  • Chapter 22. Translating Microbiome Science to Society-What's Next?
  • Index
  • Introduction
  • What Should Change-Obstacles to Linking Science and Society
  • Flawed Concepts and Bad Language
  • Unrealistic Expectations and Extrapolations from Experimental Animals
  • Challenges and Opportunities
  • Conclusion-Bold Predictions
  • Introduction
  • Human Gut Microbiota
  • Dysbiosis in Chronic Fatigue Syndrome
  • Probiotics in Chronic Fatigue Syndrome
  • Conclusion
  • Introduction
  • Diet, the Microbiome, and Irritable Bowel Syndrome
  • Probiotics in Irritable Bowel Syndrome
  • Conclusion
  • Introduction
  • Gut Microbiota Composition and Metabolic Disorders
  • Dysbiosis Associated With Metabolic Disorders
  • Prebiotic and Probiotic as Tools to Modulate Dysbiosis in Metabolic Diseases
  • Gut Microbiota, Obesity, and Behavior: The Modulation of the Gut Endocrine Function as a Key Target
  • Conclusions
  • Introduction
  • Development of the Enteric Nervous System
  • Microbial Colonization of the Gastrointestinal Tract
  • Influence of Microbiota on the Development of the Enteric Nervous System
  • Proposed Mechanisms for Microbial-Enteric Nervous System Interactions
  • Potential for Probiotic Therapy to Influence the ENS
  • Clinical Relevance
  • Conclusions
  • Alcohol and Gut Barrier Function: What Have Animal and Human Studies Taught Us?
  • Alcohol-Induced Changes on the Gut Microbiota
  • Do Changes in the Gut Influence Brain and Behavior in Alcohol Use Disorders?
  • Conclusion
  • Introduction
  • Factors Influencing Cognition
  • Probiotic Interventions and Cognitive Function
  • Prebiotic Intervention and Cognitive Function
  • Conclusions
  • Introduction
  • Gut-Brain Pathways in Schizophrenia
  • Neurodevelopment
  • Inflammation and Immunity in Schizophrenia
  • Diet and Schizophrenia
  • Metabolic Dysfunction and Schizophrenia
  • Hypothalamic-Pituitary-Adrenal Axis
  • Microbiota-Gut-Brain Interventions in Schizophrenia
  • Summary
  • Introduction
  • Autism Spectrum Disorder
  • Gastrointestinal Dysfunction in Autism Spectrum Disorder
  • Microbial Dysbiosis in Autism Spectrum Disorder
  • Probiotics in the Treatment of Neurodevelopmental Disorders
  • Other Microbiota-Related Treatments for Autism Spectrum Disorder
  • Future Studies
  • Introduction
  • The Hypothalamic-Pituitary-Adrenal Axis
  • Gut Microbiota: A Critical Factor for Determining the Hypothalamic-Pituitary-Adrenal Axis Setpoint
  • Antistress Effects of Probiotics
  • Pathways, Molecules, and Cell Types Involved in Microbiota-Gut-Brain Signaling
  • Short-Chain Fatty Acids
  • Molecular and Cellular Targets Influenced by the Microbiota, Probiotics, and Short-Chain Fatty Acids
  • Probiotics, Prebiotics, and Stress-Related Disorders
  • Conclusion and Perspectives
  • Introduction
  • Gut Microbiota and Immune System-Related Diseases
  • Gut Microbiota and Intestinal Diseases
  • Gut Microbiota and Diseases of the Nervous System
  • Gut Microbiota and Metabolic Diseases
  • Overview of Some Potential Therapies that are Currently Being Used to Re-Establish a Healthy Gut Microbiota
  • Conclusion
  • Introduction
  • Antibiotics Use Among Persons With Cystic Fibrosis
  • Long-Term Issues of Chronic Antibiotic Use
  • Modulation of the Gut Microbiota
  • Future Directions
  • Conclusion
  • Introduction
  • The Developing Microbiota in Early Life
  • Impact of Early Life Microbiota on the Development of Key Host Homeostatic Mechanisms
  • Health Outcomes Related to Perturbation of the Intestinal Microbiota in Early Life
  • Concluding Remarks
  • Introduction
  • General Features of the Microbiota
  • Microbiome Richness
  • How Habitual Diet Modulates Microbiota Diversity
  • Microbiota in the Elderly
  • Immunosenescence and Inflamm-Aging
  • Microbiome Composition in the Elderly
  • Pressures on the Aging Microbiome
  • Probiotics, Prebiotics and Other Modulators of the Microbes in the Elderly
  • Future Perspectives
  • Changes to the Food Supply and Global Impact on Health
  • Nutrients and Mental Health
  • Microbiome Nuances
  • Conclusions
  • Historical Context
  • Microbial Endocrinology: Relevance to Probiotics
  • Experimental Issues Associated with Evaluation of Probiotics for Neurochemical Production
  • Experimental Rubric to Address In Vitro to In Vivo Design Issues
  • Concluding Thoughts
  • Introduction
  • Communication Along the Microbiota-Gut-Brain Axis
  • The Microbiota-Brain-Gut Axis in Health and Disease
  • The Germ-Free Mouse
  • The Germ-Free Mouse and Health
  • Anxiety and Stress Responsivity
  • Social, Repetitive, and Locomotor Behaviors
  • Learning and Memory
  • Neurochemical and Molecular Alterations
  • Neurogenesis
  • Blood-Brain Barrier
  • Microglia
  • The Germ-Free Mouse: Strengths, Limitations, and Alternatives
  • Conclusions
  • Introduction
  • Gut Microbiota Composition in Infants and Adults
  • Factors Disrupting the Gut Microbiota
  • Prebiotics and Probiotics
  • Gut Microbiota Modulation Using Probiotics and Prebiotics
  • Conclusion
  • The Probiotic Concept and Evolution
  • Functional Food Versus Foods Bearing Nutritional or Health Claims
  • Criteria for Developing Probiotics and Claiming Their Benefits on Foods in Europe
  • Situation of Claims on Probiotic Products in Different Countries
  • Future Perspectives in the Development of Probiotics
  • Conclusions
  • Introduction
  • Probiotic Selection and Identification
  • Next-Generation Sequencing Tools
  • From Sequence to Function
  • Probiotic Safety Assessments Using Genomic Data
  • Probiogenomics
  • Conclusion
  • Regulatory Impact of Definitions
  • Gut-Brain Axis: What Could Be Relevant for Establishing Regulations?
  • Conclusions

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