The Multi-Organ Donor: A Guide to Selection, Preservation and Procurement

 
 
Current and Future Developments in Surgery (Verlag)
  • 1. Auflage
  • |
  • erschienen am 29. November 2018
  • |
  • 215 Seiten
 
E-Book | ePUB mit Adobe DRM | Systemvoraussetzungen
978-1-68108-756-6 (ISBN)
 

Advances in the science of immunology have improved the success rate of organ transplantations since the mid twentieth century. Organ transplantation is now a lifesaving medical procedure for thousands of patients around the world with end-organ diseases.

  • Englisch
  • Sharjah
  • |
  • Vereinigte Arabische Emirate
PublishDrive
  • 3,84 MB
978-1-68108-756-6 (9781681087566)
weitere Ausgaben werden ermittelt
  • Cover
  • Title
  • Biblography
  • End User License Agreement
  • Contents
  • Preface
  • List of Contributors
  • Introduction
  • Juan A. Sanchez and Robert S.D. Higgins*
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • The Organ Allocation System
  • Karen Kennedy* and Charles Alexander
  • INTRODUCTION
  • Legislative, Regulatory and Accreditation History Highlights
  • Uniform Anatomical Gift Act
  • Organ Procurement Organization Accreditation Program
  • Organ Donor Clinical Processes
  • Referral and Evaluation
  • Authorization Processes
  • Clinical Donor Management
  • Donor Management Priorities
  • Organ Allocation Overview
  • Heart and Lung Wait Lists and Allocation: Excerpts from UNOS Policies 6, 10 [2]
  • Liver Wait List and Allocation: Excerpts from UNOS Policy 9 [2]
  • Intestine Allocation Algorithm: Excerpts from UNOS Policy 7 [2]
  • Geographic Location [2]
  • Medical Urgency [2]
  • Additional Considerations
  • Kidney Wait List and Allocation: Excerpts from UNOS Policy 8 [2]
  • KDPI Score [2]
  • EPTS Score [2]
  • CPRA Percentage [2]
  • KAS System [2]
  • Kidney Allocation Points Score [2]
  • Antigen Mismatch [2]
  • Geographic Proximity
  • Double Kidney Allocation [2]
  • Pancreas Wait List and Allocation: Excerpts from UNOS Policy 11 [2]
  • CPRA Percentage [2]
  • Antigen Mismatch [2]
  • Geographic Proximity and Waiting Time
  • Kidney - Pancreas Allocation: Excerpts from UNOS Policy 11 [2]
  • ABO
  • VCA Wait List and Allocation: Excerpts from UNOS Policy 12 [2]
  • Surgical Recovery Processes
  • Follow-up Activities
  • CONCLUSION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Identification of the Brain Dead Donor
  • Justin Zamoyski and Diana Greene-Chandos*
  • INTRODUCTION
  • PATHOLOGY AND PHYSIOLOGY
  • PREPARATION FOR CLINICAL EXAM
  • Coma
  • Neuroimaging Correlates
  • Sedation Absent
  • Paralytic Absent
  • Absence of Metabolic Abnormalities
  • Normothermia
  • Normotension
  • Absence of Spontaneous Respirations
  • COMPONENTS OF BRAIN DEATH EXAMINATION
  • Pupillary Reflexes
  • Corneal Reflexes
  • Oculocephalic Reflex
  • Oculovestibular Reflex
  • Facial Noxious Stimuli
  • Pharyngeal and Tracheal Reflexes
  • Noxious Stimuli in Extremities
  • APNEA TESTING
  • ANCILLARY TESTING
  • Electrophysiological Testing
  • Vascular Imaging
  • SPECIAL CIRCUMSTANCES
  • Pediatric Patients
  • "Brainstem" Death
  • Maternal Death by Neurological Criteria
  • Religious Exceptions
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Management of Public Health Service (PHS) Increased Risk Donors and Hepatitis C or HIV Infected Donors
  • Nicole Theodoropoulos*, 1, Stephanie Pouch2 and Dorry Segev3
  • INTRODUCTION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Management of the Multi-Organ Donor and Logistic Considerations
  • Sharon Weeks*, Shane Ottmann and Andrew Cameron
  • INTRODUCTION
  • DONOR MANAGEMENT
  • Cardiovascular Dysfunction
  • Pulmonary Deterioration
  • Endocrine Derangements
  • Temperature Regulation
  • LOGISTIC CONSIDERATIONS
  • Organizational Considerations
  • Logistics of Organ Recovery
  • CONCLUSION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Current State of Organ Preservation
  • Eliza Beal, Bryan Whitson* and Sylvester Black
  • INTRODUCTION
  • Preservation Solutions
  • Classification of Preservation Solutions
  • Intracellular Vs. Extracellular Solutions
  • Impermeants
  • Antioxidants
  • Buffers
  • Energy Precursors
  • Abdominal Transplant
  • Liver Preservation
  • Renal Preservation
  • Pancreas Preservation
  • Intestinal Preservation
  • Cardiac and Pulmonary Transplant
  • Heart Transplantation
  • Lung Transplantation
  • CONCLUSION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Organ Specific Considerations: Heart
  • Vincent Nardy1, Ahmet Kilic2,* and Arman Kilic3
  • INTRODUCTION
  • Donor and Recipient Selection
  • Patient Management and Preservation Strategies
  • Procurement Technique
  • FUTURE DIRECTIONS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Organ Specific Considerations: Lung
  • Jinny Ha, Stephen Broderick and Errol Bush*
  • INTRODUCTION
  • Donor Criteria
  • Age
  • Smoking History
  • ABO Compatibility
  • Size Criteria
  • Graft Ischemia
  • Radiographic Findings
  • Bronchoscopy and Gram Stain
  • Gas Exchange
  • Techniques for Donor Lung Extraction
  • Initial On-site Evaluation of the Donor Organ
  • Positioning
  • Initial Gross Evaluation of the Donor Lungs
  • Donor Lung Dissection
  • Donor Lung Excision
  • CONCLUSIONS AND FUTURE DIRECTIONS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Liver Procurement: The Donor Hepatectomy
  • Marcos E. Pozo, Russell Wesson, Benjamin Philosophe, Andrew Cameron* and Jacqueline Garonzik-Wang
  • INTRODUCTION
  • General Considerations
  • Technique for Liver Procurement
  • Before Incision
  • Warm Dissection
  • Organ Cold Perfusion
  • Cold Dissection
  • Special Scenarios
  • Unexpected Intraabdominal Findings
  • Alternative Cannulation and Cross-Clamp Sites
  • Donation after Cardiac Death (DCD)
  • CONCLUSION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Organ Specific Considerations: Pancreas and Kidney
  • Iyore James, Ashraf El-Hinnawi and Amer Rajab*
  • INTRODUCTION
  • Donor Selection [Pancreas]
  • Donor Selection [Kidney]
  • Procurement
  • Preservation
  • CONCLUSION/FUTURE DIRECTION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Living Donation
  • Ben Philosophe1, Jaime Glorioso1, Shane Ottmann1, Iyore James1 and Amer Rajab*, 2
  • INTRODUCTION
  • Living Donor Liver Transplantation (LDLT)
  • Patient Selection
  • Surgical Technique
  • Donor Right Lobe Hepatectomy
  • Donor Left Lobe Hepatectomy
  • Donor Left Lateral Hepatectomy
  • LIVING DONATION- KIDNEY
  • Introduction
  • Benefits of Living Donor Kidney Transplant
  • Donor Evaluation
  • Operative Approach
  • Complications
  • CONCLUDING REMARKS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Pediatric Issues: Split Liver/Living Liver Donation
  • Kyle Jackson, Benjamin Philosophe and Andrew Cameron*
  • INTRODUCTION
  • SPLIT LIVER TRANSPLANTATION
  • Introduction
  • Technical Aspects
  • Donor and Recipient Selection
  • Potential Complications and Issues
  • Modern Outcomes
  • LIVING DONOR LIVER TRANSPLANTATION
  • Introduction
  • Donor Issues
  • Technical Issues
  • Potential Complications and Issues
  • Modern Outcomes
  • SUMMARY
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Islet Cell Donation
  • Jill Buss and Amer Rajab*
  • INTRODUCTION
  • Donor Characteristics
  • Donor Scoring
  • Organ Procurement
  • Organ Preservation
  • CONCLUSION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • The Future of Organ Donation: Ex Vivo Preservation
  • Eliza Beal, Sylvester Black and Bryan Whitson*
  • INTRODUCTION
  • Ex Vivo Liver Perfusion
  • Hypothermic Machine Perfusion
  • Subnormothermic Perfusion
  • Normothermic Machine Perfusion
  • Future Directions in Ex Vivo Liver Perfusion
  • Ex Vivo Lung Perfusion
  • ANIMAL MODELS
  • Porcine Models
  • Rodent Models
  • Human Observational Studies
  • Discarded Lungs
  • Biomarkers
  • Published Trials
  • Ongoing Trials
  • FUTURE DIRECTIONS
  • CONCLUSION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • The Future of Organ Donation and Transplantation: 2018 and Beyond
  • Robert S.D. Higgins*
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Subject Index
  • Back Cover

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