Imaging in Dermatology

 
 
Academic Press
  • 1. Auflage
  • |
  • erschienen am 29. Juli 2016
  • |
  • 560 Seiten
 
E-Book | ePUB mit Adobe DRM | Systemvoraussetzungen
E-Book | PDF mit Adobe DRM | Systemvoraussetzungen
978-0-12-802859-9 (ISBN)
 

Imaging in Dermatology covers a large number of topics in dermatological imaging, the use of lasers in dermatology studies, and the implications of using these technologies in research. Written by the experts working in these exciting fields, the book explicitly addresses not only current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today, along with the cellular and molecular effects of these technologies.

  • Outlines the fundamentals of imaging and lasers for dermatology in clinical and research settings
  • Provides knowledge of current and future applications of dermatological imaging and lasers
  • Coherently structured book written by the experts working in the fields covered
  • Englisch
  • San Diego
  • |
  • USA
Elsevier Science
  • 23,48 MB
978-0-12-802859-9 (9780128028599)
0128028599 (0128028599)
weitere Ausgaben werden ermittelt
  • Front Cover
  • IMAGING IN DERMATOLOGY
  • IMAGING IN DERMATOLOGY
  • Copyright
  • Dedication
  • Contents
  • List of Contributors
  • 1 - Introduction to Imaging in Dermatology
  • References
  • 2 - The Role of Clinical Photography in Dermatology
  • INTRODUCTION
  • THE EQUIPMENT
  • THE "ART" OF TAKING DERMATOLOGICAL CLINICAL PICTURES
  • WHY PHOTOGRAPHS?
  • PHOTOGRAPHS AS AN EDUCATIONAL TOOL
  • PHOTOGRAPHS AS A DIAGNOSTIC TOOL
  • THREE ADDITIONAL ASPECTS THAT NEED TO BE CONSIDERED IN THIS CONTEXT
  • PHOTOGRAPHY AS A TOOL FOR DOCUMENTATION
  • PHOTOGRAPHY AS A TOOL IN RESEARCH
  • PHOTOGRAPHS FROM THE PATIENT'S PERSPECTIVE
  • PHOTOGRAPHS FROM A LEGAL POINT OF VIEW
  • PHOTOGRAPHY AS AN INFORMATIVE TOOL FOR THE GENERAL POPULATION
  • CONCLUSIONS
  • References
  • 3 - Dermoscopy
  • INTRODUCTION
  • Dermoscopy Is an Integral Part of Clinical Examination
  • DERMOSCOPY OF MELANOCYTIC SKIN TUMORS
  • Pattern Analysis
  • Melanoma-Specific Criteria
  • Nail Pigmentation
  • DERMOSCOPY OF COMMON BENIGN NONMELANOCYTIC SKIN TUMORS
  • Seborrheic Keratosis
  • Dermatofibroma
  • Vascular Tumors
  • DERMOSCOPY OF COMMON MALIGNANT NONMELANOCYTIC TUMORS
  • Basal Cell Carcinoma
  • Keratinocyte Skin Cancer
  • Actinic Keratosis
  • Bowen Disease (Intraepidermal Carcinoma)
  • Squamous Cell Carcinoma
  • DERMOSCOPY IN GENERAL DERMATOLOGY
  • Papulosquamous Skin Diseases
  • Psoriasis
  • Dermatitis
  • Lichen Planus
  • Pityriasis Rosea
  • Granulomatous Skin Diseases
  • Discoid Lupus Erythematosus
  • Rosacea
  • Lichen Sclerosus and Morphea
  • Urticaria and Urticarial Vasculitis
  • Pigmented Purpuric Dermatoses (Capillaritis)
  • Mastocytosis
  • Mycosis Fungoides
  • Dermoscopy of Infectious Skin Diseases
  • Scabies
  • Mycoses
  • Molluscum Contagiosum
  • Pediculosis
  • CONCLUSION
  • References
  • 4 - Trichoscopy: The Dermatologist's Third Eye
  • INTRODUCTION
  • TECHNICAL CONSIDERATIONS
  • DERMOSCOPIC FEATURES
  • Follicular Signs
  • Yellow Dots
  • White Dots
  • Black Dots
  • Hair Shaft Characteristics
  • Interfollicular Patterns
  • Vascular Patterns
  • Pigment Pattern
  • TRICHOSCOPY FINDINGS IN COMMON HAIR AND SCALP CONDITIONS
  • Androgenetic Alopecia
  • Alopecia Areata
  • Tinea Capitis
  • Trichotillomania
  • Telogen Effluvium
  • Lichen Planopilaris
  • Discoid Lupus Erythematosus
  • Frontal Fibrosing Alopecia
  • Folliculitis Decalvans
  • Other Cicatricial Alopecias
  • Hair Shaft Disorders
  • Monilethrix
  • Trichorrhexis Nodosa
  • Trichorrhexis Invaginata
  • Pili Torti
  • Pili Annulati
  • Other Scalp Conditions
  • Differentiating Scalp Psoriasis From Seborrheic Dermatitis
  • CONCLUSION
  • Abbreviations
  • References
  • 5 - Dermatoscopic Correlates of Nail Apparatus Disease: A Look at the Nail From Another Scope, the Dermatoscope
  • INTRODUCTION
  • METHODS IN NAIL DERMATOSCOPY
  • DERMATOSCOPY OF NAIL PIGMENT CHANGES (CHROMONYCHIA)
  • Melanonychia
  • Nail Apparatus Melanoma
  • Melanocytic Nevus
  • Nonmelanocytic Nail Tumors
  • Melanocyte Activation
  • Subungual Hemorrhage
  • Fungal and Bacterial Nail Infection
  • Dermatoscopy in Other Causes of Chromonychia
  • Leukonychia
  • Erythronychia
  • Chloronychia
  • DERMATOSCOPY OF OTHER NAIL CHANGES
  • Nonmelanocytic Tumors of the Nail Apparatus
  • Glomus Tumor
  • Onychopapilloma
  • Onychomatricoma
  • Viral Warts
  • Bowen's Disease and Squamous Cell Carcinoma
  • Nail Trauma, Foreign Bodies, and Artifacts
  • Onychomycosis
  • Onycholysis
  • Inflammatory Nail Disease (Psoriasis, Eczema, and Lichen Planus)
  • Psoriasis
  • Lichen Planus
  • Connective Tissue Disease and Nail Fold Capillaroscopy
  • CONCLUSION
  • References
  • 6 - Optical Coherence Tomography for Skin Cancer and Actinic Keratosis
  • INTRODUCTION
  • OPTICAL COHERENCE TOMOGRAPHY
  • THE SQUAMOUS SPECTRUM
  • Optical Coherence Tomography Imaging of Actinic Keratosis
  • Imaging of Squamous Cell Carcinoma
  • BASAL CELL CARCINOMA
  • PIGMENTED NEVI AND MELANOMA
  • OTHER SKIN TUMORS
  • Lymphoma
  • Hemangiomas
  • CONCLUSION
  • Acknowledgments
  • References
  • 7 - Optical Coherence Tomography Imaging of Skin Scarring and Fibrosis
  • INTRODUCTION
  • OPTICAL COHERENCE TOMOGRAPHY IMAGING OF NORMAL SKIN COLLAGEN
  • OPTICAL COHERENCE TOMOGRAPHY IMAGING OF SKIN FIBROSIS AS A FEATURE OF SYSTEMIC SCLEROSIS
  • OPTICAL COHERENCE TOMOGRAPHY IMAGING OF FIBROTIC SCARS
  • THE FUTURE OF OPTICAL COHERENCE TOMOGRAPHY
  • CONCLUSION
  • Abbreviations
  • References
  • 8 - Polarization Speckles and Skin Applications
  • INTRODUCTION
  • Coherence
  • Polarization
  • Polarization Speckle
  • SKIN SURFACE ROUGHNESS QUANTIFICATION
  • MELANOMA SCREENING
  • ELECTRIC FIELD MONTE CARLO SIMULATION
  • CONCLUSION
  • Glossary
  • List of Acronyms and Abbreviations
  • Acknowledgments
  • References
  • 9 - New Developments in Fluorescence Diagnostics
  • INTRODUCTION
  • FLUORESCENCE HISTORY
  • FLUORESCENCE PRINCIPLES
  • FLUORESCENCE CAPTURE AND DETECTION
  • IMAGE ENHANCEMENT
  • AUTOFLUORESCENCE
  • ALTERNATIVE DETECTION METHODS
  • References
  • 10 - Ex Vivo Fluorescence Microscopy: Clinical Applications in Dermatology and Surgical Pathology
  • INTRODUCTION
  • CONTRAST AGENTS
  • INSTRUMENT AND IMAGE ACQUISITION
  • APPLICATION OF EX VIVO FLUORESCENCE MICROSCOPY IN DERMATOLOGY
  • Basal Cell Carcinoma
  • Squamous Cell Carcinoma
  • APPLICATION OF EX VIVO FLUORESCENCE MICROSCOPY IN GENERAL SURGERY
  • Oral Mucosa
  • Breast Cancer
  • Colon Cancer
  • Thyroid Cancer
  • Other Tumors
  • CONCLUSIONS
  • List of Acronyms and Abbreviations
  • References
  • 11 - Coherent Raman Scattering Microscopy in Dermatological Imaging
  • INTRODUCTION
  • Skin Structure
  • Optical Techniques Used in Dermatological Imaging
  • Wood Lamp
  • Dermoscopy
  • Reflectance Confocal Microscopy
  • Optical Coherence Tomography
  • Multiphoton Microscopy
  • Coherent Raman Scattering
  • Applications of Coherent Raman Techniques in Biomedical Research
  • IMAGING SKIN STRUCTURES USING COHERENT RAMAN SCATTERING
  • Normal Skin
  • Diseased Skin
  • IMAGING DRUG PENETRATION AND CHEMICAL DIFFUSION USING COHERENT RAMAN SCATTERING
  • Retinol and Retinoic Acid
  • Nonsteroidal Anti-inflammatory Drugs
  • Oils
  • CHALLENGES AND NEW ADVANCES OF COHERENT RAMAN TECHNIQUES IN SKIN IMAGING
  • Imaging Depth
  • Improved Contrast
  • Making Coherent Raman Imaging Accessible
  • CONCLUSIONS
  • List of Acronyms and Abbreviations
  • References
  • 12 - Rapid Real-Time Raman Spectroscopy and Imaging-Guided Confocal Raman Spectroscopy for In Vivo Skin Evaluation ...
  • INTRODUCTION
  • Raman Effect
  • Raman Spectroscopy Studies in Skin
  • Raman Spectroscopy for In Vivo Applications
  • RAPID REAL-TIME RAMAN SYSTEM
  • Instrumentation
  • System Calibration and Fluorescence Background Removal
  • Special Lighting for In Vivo Clinical Raman Measurement
  • RAPID REAL-TIME RAMAN SYSTEM FOR IN VIVO SKIN CANCER DIAGNOSIS
  • Patient Recruitment
  • Three Clinical Diagnostic Tasks
  • Multivariate Analysis: Principal Component Generalized Discriminant Analysis and Partial Least Squares
  • Receiver Operating Characteristic Curves and Diagnostic Parameters
  • Raman Spectra of Different Pathologies
  • Raman Spectroscopy Distinguishes Skin Cancers From Benign Lesions: Previous Cohort
  • Comparison With Previous Clinical and Experimental Studies: Previous Cohort
  • Independent Validation: New Cohort
  • Independent Validation: Consolidated Cohort
  • MODELING OF IN VIVO SKIN RAMAN SPECTRA
  • An Eight-Layer Normal Human Skin Model
  • Procedures of the Monte Carlo Simulation
  • Light Distribution in the Skin
  • Raman Escape Function in the Skin
  • Raman Detection Efficiency
  • Simulated Raman Spectra of In Vivo Skin
  • IMAGING-GUIDED CONFOCAL RAMAN SPECTROSCOPY FOR IN VIVO SKIN ASSESSMENT
  • Multimode Imaging-Guided Confocal Raman Instrumentation
  • Imaging-Guided Confocal Raman Spectroscopy of Blood In Vivo
  • Monitoring Glucose Level In Vivo
  • SUMMARY
  • Acknowledgments
  • References
  • 13 - Surface-Enhanced Raman Spectroscopy for Intradermal Measurements
  • INTRODUCTION
  • Intradermal Measurements and Relevant Techniques
  • Raman Spectroscopy
  • Spontaneous Raman Spectroscopy
  • Surface-Enhanced Raman Spectroscopy
  • Mechanisms of Surface-Enhanced Raman Spectroscopy
  • Electromagnetic Enhancement
  • Chemical Enhancement
  • Surface-Enhanced Raman Spectroscopy in Biomedical Applications
  • SURVEY OF INTRADERMAL SURFACE-ENHANCED RAMAN SPECTROSCOPY APPROACHES
  • Injection of Surface-Enhanced Raman Spectroscopy-Active Nanoparticles
  • Surface-Enhanced Raman Spectroscopy-Active Structures
  • Surface-Enhanced Raman Spectroscopy-Active Acupuncture Needles
  • Surface-Enhanced Raman Spectroscopy-Active Microneedles
  • Comparison Across All Methods
  • FUTURE TRENDS OF INTRADERMAL SURFACE-ENHANCED RAMAN SPECTROSCOPY DEVELOPMENT
  • CONCLUSION
  • List of Acronyms and Abbreviations
  • References
  • 14 - Broadband Coherent Anti-Stokes Raman Scattering
  • INTRODUCTION
  • BACKGROUND
  • BROADBAND COHERENT ANTI-STOKES RAMAN SCATTERING
  • THEORY
  • Vibrational Stimulation and Scattering
  • The Nonlinear Susceptibility, Nonresonant Background, and Raman Spectrum Extraction
  • EXPERIMENTAL RESULTS: TISSUE IMAGING
  • System Architecture
  • Histological Imaging
  • CONCLUSION
  • List of Abbreviations
  • Glossary
  • References
  • 15 - In Vivo Reflectance Confocal Microscopy in Dermatology
  • INTRODUCTION
  • THE TECHNOLOGY: REFLECTANCE CONFOCAL LASER MICROSCOPE
  • NORMAL SKIN UNDER REFLECTANCE CONFOCAL MICROSCOPY
  • REFLECTANCE CONFOCAL MICROSCOPY FOR PIGMENTED TUMORS
  • Acquired Melanocytic Nevi
  • Congenital Nevi
  • Dysplastic Nevi
  • Spitz Nevi
  • Melanoma
  • Superficial Spreading Type
  • Lentigo Maligna
  • Nodular Melanoma
  • Featureless and Amelantoic Melanoma
  • Diagnostic Scoring Systems for Melanoma
  • REFLECTANCE CONFOCAL MICROSCOPY FOR EPITHELIAL TUMORS
  • Basal Cell Carcinoma
  • Diagnostic Scoring Systems for Basal Cell Carcinoma
  • Classification of Basal Cell Carcinoma Subtypes With Reflectance Confocal Microscopy
  • Actinic Keratoses
  • Squamous Cell Carcinoma
  • Seborrheic Keratosis
  • REFLECTANCE CONFOCAL MICROSCOPY FOR INFLAMMATORY LESIONS
  • Psoriasis
  • Allergic and Irritant Contact Dermatitis
  • REFLECTANCE CONFOCAL MICROSCOPY FOR MONITORING TREATMENT RESPONSE OF SKIN TUMORS
  • Reflectance Confocal Microscopy for Monitoring the Response of Basal Cell Carcinoma to Therapy
  • Reflectance Confocal Microscopy for Monitoring the Response of Actinic Keratoses to Therapy
  • Reflectance Confocal Microscopy for Monitoring the Response of Lentigo Maligna to Therapy
  • REFLECTANCE CONFOCAL MICROSCOPY FOR INFESTATIONS AND INFECTIONS
  • Onychomycosis and Dermatomycosis
  • Syphilis
  • Pityriasis Folliculorum
  • Leishmaniasis
  • Virus
  • REFLECTANCE CONFOCAL MICROSCOPY APPLICATION IN COSMETICS
  • Skin Aging
  • Monitoring Cosmetic Treatment
  • CONCLUSIONS
  • List of Abbreviations
  • Acknowledgments
  • References
  • 16 - Hyperspectral and Multispectral Imaging in Dermatology
  • INTRODUCTION
  • TISSUE OPTICS PRINCIPLES
  • HYPERSPECTRAL/MULTISPECTRAL IMAGING SYSTEMS
  • Whiskbroom
  • Pushbroom
  • Staring Array
  • Filter Wheels
  • Liquid Crystal Tunable Filters
  • Acoustooptic Tunable Filters
  • Digital Micromirror Devices
  • Snapshot
  • SYSTEM PERFORMANCE
  • Spatial and Spectral Properties
  • Image Data Cube Processing for Skin Analysis
  • Effect of Number of Wavelengths
  • APPLICATIONS IN DERMATOLOGY
  • Melanoma
  • Chronic Skin Ulcers and Wound Healing
  • Advanced Treatments for Chronic Wounds
  • Bruise
  • Burn Injury
  • Eczema
  • Other Skin Imaging Applications
  • SUMMARY
  • References
  • Further Reading
  • 17 - Diffuse Reflectance Spectroscopy and Imaging
  • INTRODUCTION
  • PRINCIPLES OF DIFFUSE REFLECTANCE
  • Measurement of Diffuse Reflectance
  • Determination of Optical Properties
  • Analytical Model
  • Computational Simulations
  • Lookup Tables
  • DIFFUSE REFLECTANCE METHODS
  • Diffuse Reflectance Spectroscopy
  • Diffuse Reflectance Imaging
  • APPLICATIONS OF DIFFUSE REFLECTANCE IN DERMATOLOGY
  • Skin Cancer
  • Port Wine Stain
  • Erythema
  • Evaluation of Sunscreen
  • Burns
  • CONCLUSION
  • List of Acronyms and Abbreviations
  • Glossary
  • References
  • 18 - Spectral Imaging in Dermatology
  • OUTLINE
  • INTRODUCTION
  • SKIN SPECIMENS EX VIVO
  • SPECTRAL IMAGING OF HISTOLOGICAL SECTIONS WITH CONVENTIONAL MICROSCOPES
  • Spectral Imaging in Stained Skin Sections
  • REFLECTANCE AND ABSORBANCE SPECTROSCOPY OF INTRINSIC SKIN CONTRAST
  • Reflectance Spectroscopy in Forensic Medicine
  • Infrared Spectroscopy
  • Fourier-Transform Infrared Spectroscopy and Skin Neoplasia
  • MULTIPHOTON MICROSCOPY AND AUTOFLUORESCENCE
  • Two-Photon Excited Fluorescence
  • Melanin
  • Two-Photon Excited Fluorescence and Reactive Oxygen Species
  • SECOND HARMONIC GENERATION IMAGING IN CONJUNCTION WITH TWO-PHOTON EXCITED FLUORESCENCE
  • FLUORESCENCE LIFETIME IMAGING
  • PUMP-PROBE MICROSCOPY
  • RAMAN SPECTROSCOPY
  • Raman Spectroscopy and Skin Neoplasia
  • Raman Spectroscopy Developments
  • COMPUTATIONAL ANALYTICAL TOOLS
  • Linear Unmixing
  • Phasor Analysis
  • Denoising
  • CONCLUSION
  • List of Abbreviations
  • Acknowledgments
  • References
  • 19 - Applications of Multiphoton Microscopy in Dermatology
  • INTRODUCTION
  • MULTIPHOTON MICROSCOPY SPECTROSCOPY AND IMAGING THEORY FUNDAMENTALS
  • Multiphoton Spectroscopy
  • Two-Photon Excitation Fluorescence Microscopy
  • Summary of Advantages of Multiphoton Excitation Microscopy
  • SKIN PHOTOPHYSICAL AND PHOTOCHEMICAL PROPERTIES AND MULTIPHOTON DERMAL IMAGING
  • Skin Physiology and Endogenous Contrast Agents
  • Key Multiphoton Photodamage Mechanisms in the Skin
  • DESIGN CONSIDERATIONS OF MULTIPHOTON MICROSCOPY
  • Raster Point Scanning Multiphoton Fluorescence, Second Harmonic Generation, and Third Harmonic Generation Microscopes
  • Nonlinear Raman Microscopy for Skin Imaging
  • Temporal Focusing Wide-Field Multiphoton Microscopy
  • APPLICATIONS OF MULTIPHOTON MICROSCOPY IN DIFFERENT AREAS OF DERMATOLOGICAL STUDIES
  • Skin Cancers
  • Other Dermatological Diseases
  • Skin Aging Studies
  • Skin Regeneration Studies
  • Transdermal Transport of Drugs, Cosmetics, Sunscreens, and Nanoparticles
  • CONCLUSION
  • Acknowledgments
  • References
  • 20 - Nonlinear Microscopy in Clinical Dermatology
  • INTRODUCTION
  • THEORETICAL CONSIDERATIONS
  • Two-Photon Fluorescence Microscopy
  • Second Harmonic Generation Microscopy
  • Fluorescence Lifetime Imaging Microscopy
  • IMAGING OF EPIDERMIS
  • In Vivo Imaging of Epidermis
  • Characterization of Epidermal Layers
  • In Vivo Optical Characterization of Psoriatic Epidermis
  • IMAGING OF DERMIS
  • In Vivo Optical Characterization of Psoriatic Dermis
  • Follow-Up Observation of Collagen Remodeling After Laser Resurfacing
  • DISCUSSION
  • List of Acronyms and Abbreviations
  • Glossary
  • References
  • 21 - Noninvasive Topical In Vivo Imaging of Skin: Confocal Reflectance Microscopy and Polarized Light Imaging
  • INTRODUCTION
  • CONFOCAL REFLECTANCE
  • Two Types of Confocal Reflectance
  • Confocal Scanning Laser Microscopy
  • Optical Coherence Tomography
  • Tissue Optical Properties
  • Scattering Coefficient
  • The Anisotropy
  • Motion as a Contrast Parameter
  • POLARIZED LIGHT IMAGING
  • What is Polarized Light?
  • Depolarization by Various Tissues
  • Depolarization by Scattering
  • Depolarization by Birefringent Fibers
  • Imaging Superficial Skin Layers with Polarized Light
  • CONCLUSION
  • Glossary
  • References
  • 22 - Polarization Optical Imaging of Skin Pathology and Ageing
  • INTRODUCTION
  • OPTICAL INTERACTIONS OF LIGHT WITH SKIN
  • The Structure of Skin
  • Skin Cancers
  • Skin Ageing
  • The Optical Properties of Skin
  • Reflectance Polarization Imaging
  • Fluorescence Polarization Imaging
  • REFLECTANCE POLARIZATION IMAGING OF HUMAN SKIN
  • Polychromatic Polarization Imaging of Skin
  • Narrow Band Polarization Imaging of Skin Cancer
  • Narrow Band Polarization Imaging of Collagen
  • Dye-Enhanced Spectrally-Resolved Polarization Imaging of Skin
  • FLUORESCENCE POLARIZATION IMAGING OF HUMAN SKIN
  • Exogenous Fluorescence Polarization of Methylene Blue (MB) and Toluidine Blue (TB) for Delineation of Nonmelanoma Skin Cancers
  • Exogenous Fluorescence Polarization of Tetracycline and Demeclocycline for Delineation of Nonmelanoma Skin Cancers
  • MULTIMODAL IMAGING OF SKIN CANCERS
  • Multimodal Optical Imaging of Nonmelanoma Skin Cancers
  • Multimodal Optical Imaging of Melanoma
  • CONCLUDING REMARKS
  • References
  • 23 - Mechanical Characterization of Skin Using Surface Acoustic Waves
  • INTRODUCTION
  • BACKGROUND AND CHARACTERIZATION OF SURFACE ACOUSTIC WAVES
  • Surface Acoustic Wave Generation
  • Q-Switched Laser Pulse
  • Shaker
  • Velocity
  • Frequency Range
  • Dispersion
  • Behavior with Transverse Elasticity Alteration
  • EXPERIMENTAL GENERATION AND DETECTION OF SURFACE ACOUSTIC WAVE ON IN VIVO HUMAN SKIN
  • SIGNAL PROCESSING OF SURFACE ACOUSTIC WAVE PHASE VELOCITY DISPERSION CURVE
  • IN VIVO HUMAN SKIN ELASTICITY MEASUREMENT BY SURFACE ACOUSTIC WAVE METHOD
  • CONCLUSIONS
  • References
  • 24 - Photoacoustic Tomography in the Diagnosis of Melanoma
  • INTRODUCTION
  • MAJOR EMBODIMENTS OF PHOTOACOUSTIC TOMOGRAPHY FOR THE DIAGNOSIS OF MELANOMA
  • PHOTOACOUSTIC TOMOGRAPHY IN THE DIAGNOSIS OF MELANOMA
  • Measuring Melanoma Thicknesses
  • Detecting Rates of Growth
  • Locating Sentinel Lymph Nodes
  • Screening for Sentinel Lymph Nodes
  • Monitoring Circulating Tumor Cells
  • FURTHER POTENTIAL APPLICATIONS
  • Noninvasive Primary Tumor Examination
  • Label-Free Histology
  • Metastatic Tumor Detection
  • CONCLUSIONS
  • Acknowledgments
  • References
  • 25 - Ultrasound Imaging in Dermatology
  • INTRODUCTION
  • TECHNICAL CONSIDERATIONS
  • NORMAL ANATOMY
  • Skin
  • Nail
  • Hair
  • COMMON APPLICATIONS
  • Tumors
  • Benign Tumors
  • Cystic Tumors
  • Epidermal Cyst
  • Pilonidal Cyst
  • Solid Tumors
  • Pilomatrixoma
  • Dermatofibroma
  • Lipoma
  • Malignant Tumors
  • Nonmelanocytic Skin Cancer
  • Melanoma
  • Primary Tumor
  • Locoregional Staging
  • Vascular Anomalies
  • Hemangiomas
  • Vascular Malformations
  • Inflammatory Diseases
  • Psoriasis
  • Morphea
  • Hidradenitis Suppurativa
  • Hematomas-Seromas-Abscesses
  • Plantar Warts
  • Nail Conditions
  • Glomus Tumor
  • Subungual Granuloma
  • Subungual Exostosis
  • Myxoid or Synovial Cysts
  • Scalp and Hair Conditions
  • Androgenetic Alopecia
  • Tumors
  • Trichilemmal Cysts
  • Inflammation
  • Perifolliculitis Capitis Abscedens et Suffodiens
  • Cosmetic Applications
  • Fillers
  • CONCLUSION
  • References
  • 26 - Optoacoustic Imaging of Skin
  • INTRODUCTION TO THE OPTOACOUSTIC (PHOTOACOUSTIC) TECHNIQUE
  • General Overview of the Technique
  • Motivation for Optoacoustic Imaging in Dermatology: Optoacoustic Mesoscopy
  • OPTOACOUSTIC MESOSCOPY SYSTEMS FOR SKIN IMAGING
  • Overview of Early Developments
  • A Comprehensive Approach: Broadband Raster-Scan Optoacoustic Mesoscopy
  • SKIN IMAGING WITH BROADBAND RASTER-SCAN OPTOACOUSTIC MESOSCOPY
  • Anatomical Human Skin Imaging
  • Angiogenesis of Skin Tumors in Mice
  • DISCUSSION AND CONCLUSION: CHALLENGES AND PERSPECTIVES OF RASTER-SCAN OPTOACOUSTIC MESOSCOPY
  • Multispectral Raster-Scan Optoacoustic Mesoscopy
  • Instrumentation Challenges
  • Computational Challenges
  • Translation to the Clinic
  • List of Acronyms and Abbreviations
  • References
  • 27 - Use of Total Body Photography and Serial Digital Dermoscopy in Dermatology
  • INTRODUCTION
  • TOTAL BODY PHOTOGRAPHY
  • SERIAL (SEQUENTIAL) DIGITAL DERMOSCOPY
  • TOTAL BODY PHOTOGRAPHY WITH SERIAL DIGITAL DERMOSCOPY
  • CONCLUSION
  • References
  • 28 - Functional MRI Advances to Reveal the Hidden Networks Behind the Cerebral Processing of Itch
  • INTRODUCTION
  • NEUROPHYSIOLOGICAL ASPECTS OF ITCH TRANSMISSION
  • Types of Information fMRI Can Provide
  • Neuroimaging Techniques That Have Been Used to Investigate the Brain Responses Elicited by Itch
  • A BRIEF CHRONOLOGY OF BRAIN IMAGING STUDIES DEDICATED TO THE EXPLORATION OF ITCH PROCESSING
  • Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging
  • Arterial Spin Labeling
  • CEREBRAL AREAS SIGNIFICANTLY INVOLVED IN ITCH PROCESSING
  • The Differential Brain Processing of Histamine and Cowhage Itches
  • Somatosensory Areas
  • The Role of the Parietal and Frontal Associative Areas in Itch Processing
  • The Anterior Cingulate Cortex
  • Insula
  • Claustrum
  • Nucleus Accumbens and Itch Modulation
  • Septal Nuclei
  • THE ROLE OF BRAIN'S REWARD CIRCUITS IN ITCH RELIEF
  • OTHER SUBCORTICAL CENTERS INVOLVED IN ITCH PROCESSING
  • BRAIN PROCESSING OF ITCH IN PATIENTS WITH CHRONIC PRURITUS
  • CONTAGIOUS ITCH
  • CONCLUSIONS
  • References
  • 29 - Magnetic Resonance Microscopy of Skin
  • OUTLINE
  • INTRODUCTION
  • STATUS QUO FOR IN VIVO SKIN MAGNETIC RESONANCE IMAGING ON HUMANS
  • LOW-FIELD MAGNETIC RESONANCE IMAGING: FIRST STEPS TOWARDS CLINICAL ROUTINE
  • HIGH-FIELD MAGNETIC RESONANCE IMAGING: AN EX VIVO APPROACH
  • CONCLUSION
  • Glossary
  • List of Acronyms and Abbreviations
  • References
  • 30 - The Role of Magnetic Resonance Imaging in the Management of Anogenital Hidradenitis Suppurativa
  • INTRODUCTION
  • ETIOLOGY
  • PATHOGENESIS
  • CLINICAL MANIFESTATIONS
  • DIAGNOSIS
  • ASSESSMENT OF DISEASE SEVERITY
  • ROLE OF IMAGING
  • Magnetic Resonance Imaging Protocol
  • Normal Anal Anatomy on Magnetic Resonance Imaging
  • Appearances of Hidradenitis Suppurativa on Pelvic Magnetic Resonance Imaging
  • COMPARISON WITH OTHER IMAGING MODALITIES
  • MANAGEMENT
  • CONCLUSION
  • References
  • 31 - Thermal Imaging in Dermatology
  • INTRODUCTION
  • SKIN THERMAL PROPERTIES
  • Skin Structure
  • Epidermis
  • Dermis
  • Hypodermis
  • Skin Thermal Modeling
  • FUNDAMENTALS OF THERMAL IMAGING
  • Thermal Radiation Characteristics
  • Thermal Radiation Imaging Devices
  • Spectral Range
  • Detector Format
  • Camera Objectives
  • Camera Frame Rate
  • Camera Sensitivity
  • Other Parameters
  • Measurement Procedures
  • Passive Thermography
  • Active Thermography
  • Pulsed Thermography and Stepped Thermography
  • Lock-In Thermography, Pulsed-phase Thermography, and Dynamic Thermal Assessment
  • APPLICATIONS IN DERMATOLOGY
  • Burns
  • Skin Cancer
  • Other Potential Applications
  • CONCLUSION
  • List of Acronyms and Abbreviations
  • Acknowledgments
  • References
  • 32 - The Role of Positron Emission Tomography/Computed Tomography in Cutaneous Melanoma
  • BACKGROUND
  • STAGING MELANOMA AND THE ROLE OF POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY
  • Localized Disease
  • High-Risk Primary Lesions and Advanced Disease
  • THE ROLE OF POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY IN RESTAGING
  • POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY TECHNIQUE
  • COMPARISON OF POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY WITH OTHER IMAGING MODALITIES
  • CONCLUSION
  • References
  • 33 - Molecular Imaging of Merkel Cell Carcinoma
  • INTRODUCTION
  • MOLECULAR IMAGING METHODS
  • Metaiodobenzylguanidine Scintigraphy
  • Somatostatin Receptor Scintigraphy
  • 2-Deoxy-2-(18F)Fluoro-d-Glucose Positron Emission Tomography/Computed Tomography in Merkel Cell Carcinoma
  • Sentinel Node Imaging
  • CONCLUSION
  • References
  • 34 - Imaging in Merkel Cell Carcinoma
  • INTRODUCTION
  • Historical Background and Basic Findings
  • Clinical Appearance and Management of the Disease
  • ULTRASONOGRAPHY
  • Background and Technical Aspects
  • Clinical Application and Appearance
  • Clinical Data
  • Take-Home Message
  • COMPUTED TOMOGRAPHY
  • Background and Technical Aspects
  • Clinical Application and Appearance
  • Clinical Data
  • Take-Home Message
  • MAGNETIC RESONANCE IMAGING
  • Background and Technical Aspects
  • Clinical Application and Appearance
  • Clinical Data
  • Take-Home Message
  • LYMPHOSCINTIGRAPHY AND SENTINEL LYMPH NODE BIOPSY
  • Background and Technical Aspects
  • Clinical Application and Appearance
  • Clinical Data
  • Take-Home Message
  • List of Acronyms and Abbreviations
  • Acknowledgment
  • References
  • 35 - Imaging Evaluation of Cutaneous Lymphoma Using Functional and Structural Imaging
  • INTRODUCTION
  • MYCOSIS FUNGOID AND SEZARY SYNDROME
  • NONMYCOSIS FUNGOIDES/SEZARY SYNDROME CUTANEOUS MALIGNANT LYMPHOMA
  • EVALUATING TUMOR BIOLOGY AND BEHAVIOR AND ASSESSING RESPONSE TO TREATMENT AND OUTCOME
  • QUANTIFICATION OF PRIMARY CUTANEOUS LYMPHOMA BY 18F-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY IMA ...
  • CONCLUSION
  • References
  • 36 - Imaging Cutaneous Squamous Cell Carcinoma of the Head and Neck
  • INTRODUCTION
  • CLINICAL PRESENTATION
  • Horizontal Size
  • Depth of Invasion
  • Histological Differentiation
  • Tumor Location
  • IMAGING OF THE PRIMARY LESION
  • Evaluation of Bone and Cartilage Invasion
  • Imaging Evaluation of Perineural Tumor Spread
  • Imaging Evaluation of Squamous Cell Carcinomas of the Ear
  • Imaging for Squamous Cell Carcinomas of the Periorbital Region
  • IMAGING FOR REGIONAL AND DISTANTLY METASTATIC DISEASE
  • CONCLUSION
  • List of Acronyms and Abbreviations
  • Glossary
  • References
  • 37 - Imaging Patterns of Metastatic Melanoma
  • INTRODUCTION
  • IMAGING TECHNIQUES
  • Ultrasound
  • Radiography
  • Computed Tomography
  • Magnetic Resonance Imaging
  • Positron Emission Tomography
  • SPECT
  • METASTATIC INVOLVEMENT OF THE DIFFERENT ORGAN SYSTEMS
  • Skin, Subcutaneous Tissue, and Regional Lymph Nodes
  • Chest
  • Central Nervous System
  • Brain
  • Spine
  • Abdomen
  • Musculoskeletal System
  • Bone
  • Muscle
  • Eye
  • Other
  • CONCLUSION
  • List of Acronyms and Abbreviations
  • References
  • 38 - From Image to Information: Image Processing in Dermatology and Cutaneous Biology
  • INTRODUCTION
  • PURPOSE OF SKIN IMAGE PROCESSING
  • MOTIVATION FOR IMAGING IN DERMATOLOGY
  • TRENDS IN SKIN IMAGING AND IMAGE PROCESSING
  • PROGRESS IN SKIN IMAGING TECHNIQUES
  • Digital Imaging
  • Dermoscopy
  • Reflectance Confocal Microscopy/Confocal Scanning Laser Imaging
  • Spectral, Multispectral, and Hyperspectral Imaging
  • Optical Coherence Tomography and Multiphoton Tomography
  • Thermal Imaging
  • Photoacoustic Imaging
  • SKIN IMAGE PROCESSING
  • General Strategy
  • Category 1: Irritant Dermatitis, Erythema, and General Skin Structure
  • Digital Imaging
  • Multispectral Imaging
  • Multiphoton Tomography
  • Category 2: Wounds, Burns, and Ulcers
  • Digital Imaging
  • Hyperspectral Imaging
  • Category 3: Melanoma, Pigmented Lesions, Basal Cell Carcinoma, and Photoaging
  • Dermoscopy
  • Reflectance Confocal Microscopy
  • Multispectral Imaging
  • Multiphoton Tomography
  • Category 4: Vascular Lesions
  • Thermal Imaging
  • Photoacoustic Imaging
  • CONCLUSIONS
  • FUTURE PERSPECTIVE
  • List of Acronyms and Abbreviations
  • Glossary
  • Acknowledgments
  • References
  • Index
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Back Cover

Dateiformat: EPUB
Kopierschutz: Adobe-DRM (Digital Rights Management)

Systemvoraussetzungen:

Computer (Windows; MacOS X; Linux): Installieren Sie bereits vor dem Download die kostenlose Software Adobe Digital Editions (siehe E-Book Hilfe).

Tablet/Smartphone (Android; iOS): Installieren Sie bereits vor dem Download die kostenlose App Adobe Digital Editions (siehe E-Book Hilfe).

E-Book-Reader: Bookeen, Kobo, Pocketbook, Sony, Tolino u.v.a.m. (nicht Kindle)

Das Dateiformat EPUB ist sehr gut für Romane und Sachbücher geeignet - also für "fließenden" Text ohne komplexes Layout. Bei E-Readern oder Smartphones passt sich der Zeilen- und Seitenumbruch automatisch den kleinen Displays an. Mit Adobe-DRM wird hier ein "harter" Kopierschutz verwendet. Wenn die notwendigen Voraussetzungen nicht vorliegen, können Sie das E-Book leider nicht öffnen. Daher müssen Sie bereits vor dem Download Ihre Lese-Hardware vorbereiten.

Weitere Informationen finden Sie in unserer E-Book Hilfe.


Dateiformat: PDF
Kopierschutz: Adobe-DRM (Digital Rights Management)

Systemvoraussetzungen:

Computer (Windows; MacOS X; Linux): Installieren Sie bereits vor dem Download die kostenlose Software Adobe Digital Editions (siehe E-Book Hilfe).

Tablet/Smartphone (Android; iOS): Installieren Sie bereits vor dem Download die kostenlose App Adobe Digital Editions (siehe E-Book Hilfe).

E-Book-Reader: Bookeen, Kobo, Pocketbook, Sony, Tolino u.v.a.m. (nicht Kindle)

Das Dateiformat PDF zeigt auf jeder Hardware eine Buchseite stets identisch an. Daher ist eine PDF auch für ein komplexes Layout geeignet, wie es bei Lehr- und Fachbüchern verwendet wird (Bilder, Tabellen, Spalten, Fußnoten). Bei kleinen Displays von E-Readern oder Smartphones sind PDF leider eher nervig, weil zu viel Scrollen notwendig ist. Mit Adobe-DRM wird hier ein "harter" Kopierschutz verwendet. Wenn die notwendigen Voraussetzungen nicht vorliegen, können Sie das E-Book leider nicht öffnen. Daher müssen Sie bereits vor dem Download Ihre Lese-Hardware vorbereiten.

Weitere Informationen finden Sie in unserer E-Book Hilfe.


Download (sofort verfügbar)

128,52 €
inkl. 19% MwSt.
Download / Einzel-Lizenz
ePUB mit Adobe DRM
siehe Systemvoraussetzungen
PDF mit Adobe DRM
siehe Systemvoraussetzungen
Hinweis: Die Auswahl des von Ihnen gewünschten Dateiformats und des Kopierschutzes erfolgt erst im System des E-Book Anbieters
E-Book bestellen

Unsere Web-Seiten verwenden Cookies. Mit der Nutzung des WebShops erklären Sie sich damit einverstanden. Mehr Informationen finden Sie in unserem Datenschutzhinweis. Ok