Nutraceuticals in Veterinary Medicine

 
 
Springer (Verlag)
  • erschienen am 21. Mai 2019
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  • XIX, 877 Seiten
 
E-Book | PDF mit Adobe DRM | Systemvoraussetzungen
E-Book | PDF mit Wasserzeichen-DRM | Systemvoraussetzungen
978-3-030-04624-8 (ISBN)
 

This unique work compiles the latest knowledge around veterinary nutraceuticals, commonly referred to as dietary supplements, from ingredients to final products in a single source. More than sixty chapters organized in seven sections collate all related aspects of nutraceutical research in animal health and disease, among them many novel topics: common nutraceutical ingredients (Section-I), prebiotics, probiotics, synbiotics, enzymes and antibacterial alternatives (Section-II), applications of nutraceuticals in prevention and treatment of various diseases such as arthritis, periodontitis, diabetes, cognitive dysfunctions, mastitis, wounds, immune disorders, and cancer (Section-III), utilization of nutraceuticals in specific animal species (Section-IV), safety and toxicity evaluation of nutraceuticals and functional foods (Section-V), recent trends in nutraceutical research and product development (Section-VI), as well as regulatory aspects for nutraceuticals (Section-VII). The future of nutraceuticals and functional foods in veterinary medicine seems bright, as novel nutraceuticals will emerge and new uses of old agents will be discovered.

International contributors to this book cover a variety of specialties in veterinary medicine, pharmacology, pharmacognosy, toxicology, chemistry, medicinal chemistry, biochemistry, physiology, nutrition, drug development, regulatory frameworks, and the nutraceutical industry. This is a highly informative and carefully presented book, providing scientific insight for academia, veterinarians, governmental and regulatory agencies with an interest in animal nutrition, complementary veterinary medicine, nutraceutical product development and research.


1st ed. 2019
  • Englisch
  • Cham
  • |
  • Schweiz
Springer International Publishing
  • 54
  • |
  • 66 farbige Abbildungen, 54 s/w Abbildungen
  • |
  • 54 schwarz-weiße und 66 farbige Abbildungen, Bibliographie
  • 25,42 MB
978-3-030-04624-8 (9783030046248)
10.1007/978-3-030-04624-8
weitere Ausgaben werden ermittelt

Dr. Ramesh C. Gupta serves as Professor and Head of the Toxicology Department at the Murray State University Breathitt Veterinary Center. He earned his DVM, MVSc, and PhD in India, and carried out his postdoctoral training at Michigan State University and Vanderbilt University, US. His research has addressed experimental brain research in relation to pesticide toxicity and neurological diseases; he has further been heavily engaged in veterinary nutraceuticals research. Dr. Gupta has held worldwide presentations and served on the panels of NIH, CDC, NIOSH, and NAS. He has published >400 publications, including 7 major books. In 2006, he received the Murray State University Distinguished Researcher Award; and in 2014, the Outstanding Research Award. He is a Diplomate of the American Board of Toxicology, and Fellow of the American College of Toxicology, American College of Nutrition, and Academy of Toxicological Sciences. Currently, he holds active membership in more than a dozen academic societies.

Dr. Ajay Srivastava is Chief Scientific Officer at Vets Plus Inc., and serves as an adjunct Faculty member at University of Wisconsin-Stout, Menomonie, US. He is specialized in preclinical and clinical product development and nutraceutical research. After receiving his BS in Biological Sciences, Dr. Srivastava earned his DVM from the School of Veterinary Medicine at GB Pant University of Agriculture and Technology, India, before pursuing his MS in Pharmacology. He completed his PhD in Neuropharmacology from All India Institute of Medical Sciences, New Delhi. After his post-doctoral training in preclinical drug development in neurological disorders, Dr. Srivastava became Senior Research Scientist of the Anticonvulsant Drug Development Program at the University of Utah, where he developed a novel animal model of pharmacoresistant epilepsy to screen potential antiepileptic drugs. He is one of the pioneer researchers who discovered the role of nutraceuticals resveratrol and melatonin in epilepsy. Dr. Srivastava has chaired various scientific sessions in AVMA and WVC meetings and has published several research articles in peer reviewed journals. He has contributed chapters in textbooks on epilepsy, toxicology and nutraceuticals.

Mr. Rajiv Lall is the Founder and CEO of Vets Plus, Inc., an international leader in the animal health industry. He graduated with two masters degrees, the first in Botany from his native country of India, and the second in Pharmacognosy/Medicinal Chemistry from the University of Minnesota. His research focused on identifying, analyzing, and extracting natural ingredients from plants and plant tissue cultures that provide natural health and medicinal properties, as well as on enzymes in relation to cancer cells through animal cell cultures. Mr. Lall started his career in the human health food industry with an emphasis on probiotics. His relentless drive continues to champion animal health through scientific research and the development of nutritional products and pharmaceuticals, and through these efforts he has obtained various patents and developed several hundred products. His company, Vets Plus, Inc. is a research and science-based product development company with a strong quality and manufacturing platform to support partners in Europe and around the world. Recent awards include the Pet Age Icon Award (2015), NASC Visibility Award (2015), and Menomonie Area Chamber of Commerce Business of the Year Award (2015). Vets Plus Inc. was also nominated for Wisconsin Manufacturer of the Year in 2015. In support of the animal health industry, Mr. Lall is now Founder and CEO of Noble Pharma, LLC, a pharmaceutical company in Menomonie, Wisconsin. Mr. Lall and his wife Swati are involved in philanthropic efforts and through that they have developed the Raj and Swati Lall Microbiology Laboratory at the University of Wisconsin-Stout in support of future scientists and business leaders and the community in Menomonie, Wisconsin.

PRELIMINARY _03_2018


Introduction Ramesh C. Gupta, Murray State University, Hopkinsville, KY, USA; and Ajay Srivastava and Rajiv Lall, Vets Plus Inc, Menomonie, WI, USA Email: rgupta@murraystate.edu; drajay@vets-plus.com; lallr@vets-plus.com
I. COMMON NUTRACEUTICALS
1. Curcumin/Turmeric Naresh Chand, National Institutes of Health, Bathesda, MD, USA Email: nchand@mail.nih.gov And Sally Frautschy, University of California Los Angeles, Los Angeles, CA, USA Email: sfrautschy@mednet.ucla.edu
2. Fenugreek Dinesh Kumar, W. Ramdas Singh, Anu Rahal, and Jitendra K. Malik Indian Veterinary Research Institute, Izatnagar, Bareilly, India Email: dineshks17@gmail.com
3. Ashwagandha Vijay K. Bharti, Jitendra K. Malik, and Ramesh C. Gupta Defense Institute of High Altitude Research (DIHAR), DRDO, Leh, India Email: vijaykbharti@rediffmail.com
4. Shilajit Shailesh K. Bhavsar*, Aswim M. Thaker, and Jitendra K. Malik Anand Agricultural University, Anand, India Email: skbhavsar@yahoo.com
5. Seabuckthorne and Apricot Vijay K. Bharti Defense Institute of High Altitude Research (DIHAR), DRDO, Leh, India Email: vijaykbharti@rediffmail.com
6. Ginger Shyam S. Sharma and K. Srinivasan, Dept. Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar, Mohali, India Email: sssharma@niper.ac.in
7. Neem extract Jitendra K. Malik, Former Joint Director (Research), and Head of the Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Bareilly, Dehradun, Uttarakhand, India Email: jkmalik48@gmail.com
8. Omega fatty acids Szabina A. Stice, Division of Biotechnology and GRAS Notice Review, FDA, College Park, MD, USA E-mail: szabina.stice@fda.hhs.gov
9. L-Tryptophan and 5-HTP Ajay Srivastava, Vets Plus Inc, Menomonie, WI, USA Email: drajay@vets-plus.com
10. Berberine Ramesh C. Gupta, Murray State University, Hopkinsville, KY, USA Email: rgupta@murraystate.edu
11. Glucosinolates and organosulfur compounds Karyn Bischoff, Cornell University, Ithaca, NY, USA Email: klb72@cornell.edu
12. Nutraceutical values of red mold rice for anti-diabetic and anticlastogenic properties Jacob A. C. Sanchez, Pampanga State Agricultural University, Pampanga, Philippines Email: jacobsanchezph1@gmail.edu
13. Medium Chain Triglycerides Yet to be assigned Email:
14. Colostrum and Immunoglobulins Dan Duberdieu, Vets Plus Inc, Menomonie, WI, USA Email: dand@vets-plus.com
15. Herbal Marijuana/Cannabis sativa Joshua A. Hartsel, Delta-9 Technologies, LLC, Lake Forest, CA, USA Email: jhartsel@gmail.edu 16. Juniper Rajinder Raina, Pawan K. Verma, Jitendra K. Malik, and Ramesh C. Gupta Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, Jammu, India Email: drrajinderraina@ymail.com
17. Natural preservatives and food additives Ajay Srivastava and Tapan Gor, Vets Plus Inc, Menomonie, WI, USA Email: drajay@vets-plus.com
18. Antioxidants in animal health Yogendra K. Gupta, All India Institute of Medical sciences. New Delhi, India Email: ykgykg@gmail.com or ykg@hotmail.com 19. Polyphenols and flavonoids Satish K. Garg, Soumen Choudhury and Amit Shukla U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura, India Email: profsatish@gmail.com
II. PREBIOTICS, PROBIOTICS, SYNBIOTICS, AND ANTIMICROBIALS
20. Prebiotics and probiotics in feed and animal health Arturo Anadon, Universidad Complutense de Madrid, Madrid, Spain Email: anadon@vet.ucm.es
21. Synbiotics in animals health Jitendra K. Malik and Ramesh C. Gupta Former Joint Director (Research), and Head of the Division of Pharmacology and Toxicology, Indian Veterinary Research Institute, Bareilly, Dehradun, Uttarakhand, India Email: jkmalik48@gmail.com
22. Enzymes in feed and animal health Arturo Anadon, Universidad Complutense de Madrid, Madrid, Spain Email: anadon@vet.ucm.es
23. Optimization of mineral supplements for maximized animal productivity Jeffery O. Hall, Utah State University, Logan, UT, USA Email: jeffery.hall@usu.edu
24. Nutraceuticals used as antibacterial alternatives in animal health Arturo Anadon, Universidad Complutense de Madrid, Madrid, Spain Email: anadon@vet.ucm.es
25. Feed additives in animal health Prafull Kumar and M.J. Saxena, Ayurvet, Ghaziabad, UP, India Email: pverma@ayurvet.com; mjsaxena@ayurvet.com


III. NUTRACEUTICALS IN ORGAN/SYSTEM DISORDERS
26. Nutraceuticals in arthritis Ramesh C. Gupta, Murray State University, Hopkinsville, KY, USA E-mail: rgupta@murraystate.edu
27. Nutraceuticals in oral health and periodontal diseases Yet to be assigned Email:
28. Nutraceuticals in gastrointestinal conditions Jamil Talukder, Vets Plus Inc, Menomonie, WI, USA Email: jamilt@vets-plus.com
29. Nutraceuticals in hepatic and pancreatic diseases Sharon Gwaltney-Brant, University of Illinois, Urbana-Champaign, IL, USA Email: sharon.brant@mchsi.com
30. Nutraceuticals in genitourinary diseases Robert W. Coppock, Toxicologist and Assoc Ltd, Vegreville, AB, Canada, USA Email: r.coppock@toxicologist.ca
31. Nutraceuticals in cardiovascular diseases Csaba Zoltani, Emeritus US Army Research Lab, Aberdeen Proving Ground, MD, USA Email: c.zoltani@gmail.com
32. Nutraceuticals in respiratory diseases Ajay Srivastava, Vets Plus Inc, Menomonie, WI, USA Email: drajay@vets-plus.com
33. Nutraceuticals in reproductive disorders Moges Woldemeskel, College of Veterinary Medicine, University of Georgia, GA, USA Email: mwoldem@uga.edu
34. Nutraceuticals in dermatological disorders Moges Woldemeskel, College of Veterinary Medicine, University of Georgia, GA, USA Email: mwoldem@uga.edu
35. Nutraceuticals in mastitis Robert W. Coppock, Toxicologist and Assoc Ltd, Vegreville, AB, Canada, USA Email: r.coppock@toxicologist.ca
36. Nutraceuticals in immune disorders Moges Woldemeskel, College of Veterinary Medicine, University of Georgia, GA, USA Email: mwoldem@uga.edu
37. Nutraceuticals for wound healing Ajay Srivastava, Vets Plus Inc, Menomonie, WI, USA Email: drajay@vets-plus.com
38. Nutraceuticals for calming and stress Yet to be assigned Email:
39. Nutraceuticals for cognitive dysfunction Ramesh C. Gupta, Murray State University, Hopkinsville, KY, USA Email: rgupta@murraystate.edu
40. Nutraceuticals for antiaging Yet to be assigned Email:
41. Nutraceuticals in cancer prevention and cure Subhash C. Gupta, Banaras Hindu University, Banaras, UP, India Email: subhashg167@gmail.com
42. Nutraceuticals alone or in combination with chemotherapeutic agents for prevention and treatment of cancer M. Waheed Roomi, Dr Rath Research Institute, Santa Clara, CA, USA Email: w.roomi@drrath.com
43. Nutraceuticals in obesity and metabolic disorders Rhian B. Cope, Health Product Regulation Group, Woden ACT, Australia Email: rhian.Cope@health.gov.au
44. Nutraceuticals for ticks, fleas and other ectoparasites Ramesh C. Gupta, Murray State University, Hopkinsville, KY, USA Email: rgupta@murraystate.edu
45. Nutraceuticals in hunting, sporting and performance enhancing activities Yet to be assigned Email:
IV. NUTRACEUTICALS IN SPECIFIC ANIMAL SPECIES
46. Nutraceuticals in cattle health and diseases Ayhan Filazi and Begum Yurdakok Dikmen, Ankara University, Ankara, Turkey Email: afilazi@gmail.com
47. Nutraceuticals in equine health and diseases Yet to be assigned Email:
48. Nutraceuticals in camelids Tarun K. Gahlot, Bikaner Veterinary Science University, Bikaner, India Email: tkcamelvet@yahoo.com
49. Nutraceuticals in poultry health and diseases Begum Yurdakok Dikmen and Ayhan Filazi, Ankara University, Ankara, Turkey Email: byurdakok@yahoo.com

V. SAFETY AND TOXICITY EVALUATION OF FUNCTIONAL FOODS AND NUTRACEUTICALS
50. Safety and toxicity evaluation of nutraceuticals in animal models Nikolay Goncharov, Russian Academy of Sciences, Saint Petersburg, Russia Email: ngoncharov@gmail.com
51. Safety and toxicity evaluation of nutraceuticals using alternative in vitro models Subhash C. Gupta, Banaras Hindu University, Banaras, UP, India Email: subhashg167@gmail.com
52. Safety of pet food, functional food, and nutraceuticals Sandra James-Yi, Now Health Group, Inc., Bloomingdale, IL, USA Email: Sandra.james-yi@nowfoods.com
53. Hydrocolloids: safety and toxicity considerations Larry J. Thompson, Nestle Purina PetCare, St. Louis, MO, USA Email: larry.thompson@rdmo.nestle.com
54. Biomarkers for selected foods and nutraceuticals Ramesh C. Gupta, Murray State University, Hopkinsville, KY, USA Email: rgupta@murraystate.edu
55. Toxic interaction of nutraceuticals with food and pharmaceuticals Ramesh C. Gupta, Murray State University, Hopkinsville, KY, USA Email: rgupta@murraystate.edu Rhian B. Cope, Health Product Regulation Group, Woden ACT, Australia Email: rhian.Cope@health.gov.au

VI. NUTRACEUTICAL PRODUCT DEVELOPMENT
56. Nutraceuticals palatability process and study Ajay Srivastava, Vets Plus Inc, Menomonie, WI, USA Email: drajay@vets-plus.com
57. Steps to conduct nutraceutical clinical efficacy trials Isabelle Mougeot, CanCog technologies Inc, Toronto, ON, Canada Email: isabellem@cancog.com
58. Nutraceuticals stability study Dan Duberdieu, Vets Plus Inc, Menomonie, WI, USA Email: dand@vets-plus.com

VII. NEWER TRENDS IN NUTRACEUTICAL RESEARCH
59. Nanosupplements and animal health Francesca Caloni, Universita degli Studi di Milano, Milan, Italy Email: francesca.caloni@unimi.it
60. Fabrication and use of nanoparticles in delivery of dietary ingredients and nutraceuticals to biological system Gianfranco Risuleo, Sapienza University of Rome, Rome, Italy Email: gianfranco.risuleo@gmail.com
61. Proteomics in evaluation of nutraceuticals and functional food Christina R. Wilson, Dept. Comparative Pathology, Purdue University, West Lafayette, IN, USA Email: wilsonc@purdue.edu
62. Bioavailability of nutraceuticals Gianfranco Risuleo, Sapienza University of Rome, Rome, Italy Email: gianfranco.risuleo@gmail.com


VIII. REGULATORY ASPECT OF NUTRACEUTICALS
63. Role of AAFCO in functional food and nutraceutical regulations Anita Sinha and Bill Bookout , Vets Plus Inc, Menomonie, WI, USA Email: anitas@vets-plus.com and b.bookout@nasc.cc
64. Role of NASC in functional food and nutraceutical regulations Bill Bookout and Anita Sinha, Vets Plus Inc, Menomonie, WI, USA Email: b.bookout@nasc.cc and anitas@vets-plus.com
65. Regulatory guidelines for nutraceuticals in the EU Doriana Tedesco, Milano University, Milano, Italy Email: Doriana.tedesco@unimi.it
66. US FDA's perspective in regulation of veterinary nutraceuticals Daljit Vudathala, University of Pennsylvania, Kennet Square, PA, USA Email: vudathal@vet.upenn.edu
67. Regulatory guidelines for nutraceuticals in Australia and New Zealand Rhian B. Cope, Health Product Regulation Group, Woden ACT, Australia Email: rhian.Cope@health.gov.au
68. Regulatory guidelines for nutraceuticals and food supplements in India Pawan K. Gupta, Bareilly, India Email: drpkg_brly@yahoo.co.in
69. Regulatory guidelines for nutraceuticals in China Yet to be assigned Email:
70. Regulatory guidelines for nutraceuticals and food supplements in Turkey Begum Yurdakok Dikmen, and Ayhan Filazi, Ankara University, Ankara, Turkey Email: byurdakok@yahoo.com
71. Uses and regulatory guidelines of nutraceuticals in Philippines Jacob A. C. Sanchez, Pampanga State Agricultural University, Pampanga, Philippines Email: jacobsanchezph1@gmail.com
72. Regulatory guidelines for nutraceuticals in South America Yet to be assigned Email:
73. Regulatory guidelines for nutraceuticals in South Africa Vinny Naidoo, University of Pretoria, Onderstepoort, Republic of South Africa Email: vinny.naidoo@up.ac.za

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