Mustard Lung

Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients
 
 
Academic Press
  • 1. Auflage
  • |
  • erschienen am 3. Mai 2016
  • |
  • 162 Seiten
 
E-Book | ePUB mit Adobe DRM | Systemvoraussetzungen
E-Book | PDF mit Adobe DRM | Systemvoraussetzungen
978-0-12-803979-3 (ISBN)
 

Mustard Lung: Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients brings together the details regarding pathophysiology, medication, and protective issues to provide a comprehensive look at health problems associated with sulfur mustard injury. It provides a bench-to-bedside look at the long term complications of vesicant exposure in humans as well as how mustard gas exposure affects lung function. By providing guidelines and approaches for the diagnosis, pathogenesis, and treatment of SM injury cases, this book is helpful for a wide range of medical researchers and clinicians.

For decades, chemical respiratory disorders were diagnosed and managed traditionally similar to other chronic respiratory diseases. However, the exact nature of chemical respiratory disorders is different and needs to be treated as such.


  • Includes the most up-to-date basic and clinical research findings on sulfur mustard from top researchers
  • Provides information on chemical agents, complications that arise due to sulfur mustard exposure, and drugs available to treat injuries
  • Contains an appendix with practical prescription recommendations for patients affected by mustard lung
  • Provides a bench-to-bedside look at the long term complications of vesicant exposure in humans as well as how mustard gas exposure affects lung function


Professor Mostafa Ghanei, MD, has been practicing as a pulmonologist since 1997. He is now Vice Chancellor in Research of Ministry of Health of Iran and Head of Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University. Additionally, he is a member of the European Respiratory Society, Iranian Lung Society, Iranian Executive Board of Lung Society, National Board Exam in Respiratory Medicine, American College of Chest Physicians, and American Thoracic Society.
From 2005-15, Dr. Ghanei produced 144 documents including articles, books, editorial, letters and reviews. He has published the majority of his work (50%) in the Medicine category. He has 1,551 citations and has experience with international, national and institutional collaboration with more than 150 colleagues. He holds an h-index of 22.
  • Englisch
  • San Diego
  • |
  • USA
Elsevier Science
  • 2,40 MB
978-0-12-803979-3 (9780128039793)
0128039795 (0128039795)
weitere Ausgaben werden ermittelt
  • Front Cover
  • Mustard Lung
  • Mustard Lung: Diagnosis and Treatment of Respiratory Disorders in Sulfur Mustard-Injured Patients
  • Copyright
  • Contents
  • Preface
  • 1 - History of Chemical Weapons Use
  • REFERENCES
  • 2 - Classification of Chemical Warfare Agents and Properties of Sulfur Mustard
  • DEFINITION AND CLASSIFICATION OF CHEMICAL WARFARE AGENTS
  • PHYSICAL AND CHEMICAL PROPERTIES OF SULFUR MUSTARD
  • REFERENCES
  • 3 - Biochemical and Cellular-Molecular Mechanisms of Injury From Mustard Gas
  • THE MECHANISM OF INJURY IN THE ACUTE PHASE
  • PATHOPHYSIOLOGY OF MUSTARD GAS INJURY
  • INFLAMMATION
  • OXIDATIVE STRESS
  • APOPTOSIS
  • INCREASED PROTEOLYTIC ACTIVITY
  • DNA Damage
  • ROLE OF IMMUNE CELLS IN CHEMICALLY INJURED PATIENTS
  • GRANULOCYTES
  • MONOCYTES AND MACROPHAGES
  • T CELLS
  • CHANGES IN ANTIBODIES
  • REFERENCES
  • 4 - The Effects of Mustard Gas on Pulmonary Function and Structure
  • LONG-TERM CLINICAL AND HISTOLOGICAL EVALUATION OF INDIVIDUALS EXPOSED TO MUSTARD GAS
  • CHANGES OF THE RESPIRATORY TRACTS DUE TO MUSTARD GAS
  • UPPER RESPIRATORY TRACT
  • TRACHEOBRONCHOMALACIA AND AIR TRAPPING FOLLOWING EXPOSURE TO MUSTARD GAS
  • BASICS OF PULMONARY FUNCTION TESTS
  • GAS EXCHANGE CAPACITY OF THE LUNG
  • BRONCHIAL CHALLENGE TESTING
  • CARDIOPULMONARY EXERCISE TESTING
  • POLYSOMNOGRAPHY
  • PULMONARY GAS EXCHANGE
  • RESULTS OF PULMONARY FUNCTION TESTING IN CHEMICAL PATIENTS
  • PULMONARY FUNCTION TESTING IN SUBCLINICAL CONTACT WITH MUSTARD GAS
  • PULMONARY FUNCTION TESTING IN SYMPTOMATIC CHEMICAL PATIENTS
  • EVALUATION OF THE RELATIONSHIP BETWEEN FATIGUE AND SPIROMETRIC PARAMETERS IN CHEMICAL PATIENTS WITH RESPIRATORY DISORDERS
  • CARDIOPULMONARY EXERCISE TESTING IN SYMPTOMATIC CHEMICAL PATIENTS
  • REFERENCES
  • 5 - Signs and Symptoms of Exposure to Mustard Gas
  • SYMPTOMS OF THE ACUTE PHASE
  • LATE SYMPTOMS OF EXPOSURE TO MUSTARD GAS
  • UPPER AIRWAYS
  • LOWER AIRWAYS
  • CHRONIC COUGH
  • PREVALENCE AND DIAGNOSIS OF EMPHYSEMA IN CHEMICAL PATIENTS
  • CARCINOGENIC PROPERTIES OF MUSTARD GAS
  • OTHER INJURIES OF PULMONARY AIRWAYS AND PARENCHYMA
  • ACCUMULATION OF SECRETIONS IN THE AIRWAYS
  • IMPAIRMENT OF VENTILATION AND PERFUSION
  • AIRWAYS BLEEDING (HEMOPTYSIS)
  • BIOCHEMICAL ABNORMALITIES OF THE LUNG
  • PULMONARY VASCULAR INJURY
  • IMPAIRMENT OF PULMONARY IMMUNE CELLS
  • SIGNS AND SYMPTOMS OF OCULAR LESIONS
  • SIGNS AND SYMPTOMS OF SKIN LESIONS
  • NONSPECIFIC SYMPTOMS OF MUSTARD GAS
  • REFERENCES
  • 6 - Gastroesophageal Reflux in Chemical Patients
  • CHRONIC PULMONARY DISEASE AND GASTROESOPHAGEAL REFLUX
  • MECHANISMS INVOLVED IN THE PATHOGENESIS OF REFLUX AND PULMONARY DISEASES
  • GASTROESOPHAGEAL REFLUX IN CHEMICAL PATIENTS
  • CONCLUSIONS
  • REFERENCES
  • 7 - Diagnostic Methods in Chemical Patients
  • Laboratory Findings
  • URINE SAMPLE
  • BLOOD SAMPLES
  • OTHER SAMPLES
  • PARACLINICAL FINDINGS
  • RADIOLOGY
  • CHEST X-RAY
  • Chest X-ray Findings in Asymptomatic Patients
  • Chest X-ray Findings in Symptomatic Patients
  • PULMONARY PERFUSION SCAN
  • PULMONARY CT SCAN
  • LUNG HRCT IN ASYMPTOMATIC PATIENTS
  • HRCT IN SYMPTOMATIC PATIENTS
  • AIRWAY STENOSIS IN PULMONARY SCAN
  • CARDIOPULMONARY TESTING IN SYMPTOMATIC CHEMICAL PATIENTS
  • DIFFERENTIAL DIAGNOSES OF CHRONIC PULMONARY DISEASES RESULTING FROM MUSTARD GAS INJURY
  • ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE
  • BRONCHIECTASIS
  • PULMONARY FIBROSIS
  • BRONCHIOLITIS
  • AIRWAY STENOSIS
  • REACTIVE AIRWAY DYSFUNCTION SYNDROME
  • EVALUATION OF OTHER PULMONARY COMPLICATIONS
  • DISCUSSION AND CONCLUSIONS
  • REFERENCES
  • 8 - Treatment of Pulmonary Complications in Chemical Patients
  • TREATMENT IN THE ACUTE PHASE
  • PRIMARY PREVENTION
  • IDENTIFICATION OF THE CHEMICAL AGENT
  • TREATMENT IN THE CHRONIC PHASE
  • APPROACH TO PATIENTS WITH COUGH DUE TO CHEMICAL INJURY
  • MACROLIDES
  • ANTIOXIDANTS
  • N-ACETYLCYSTEINE
  • EVALUATION AND TREATMENT OF GASTROESOPHAGEAL REFLUX
  • SHORT-TERM USE OF CORTICOSTEROIDS
  • INHALED CORTICOSTEROID PLUS LONG-ACTING BETA2 AGONISTS
  • THERAPEUTIC EFFECTS OF INHALED ANTICHOLINERGICS
  • OPIOIDS
  • THERAPEUTIC EFFECTS OF INTERFERON GAMMA
  • PROTEASE INHIBITORS
  • OTHER IMMUNE MODULATING DRUGS
  • ALPHA-1 ANTITRYPSIN
  • NONINVASIVE POSITIVE-PRESSURE VENTILATION
  • TREATMENT OF PULMONARY DISEASE EXACERBATION
  • TERTIARY PREVENTION AND REHABILITATION
  • THE EFFECT OF NUTRITION ON DECREASING PULMONARY COMPLICATIONS
  • ANIMAL STUDIES
  • FUTURE TREATMENTS
  • CURCUMIN
  • HYPERTONIC SALINE
  • MANNITOL
  • REFERENCES
  • 9 - Mustard Gas and Cancer in Chemical Patients
  • OCCUPATIONAL EXPOSURE
  • EXPOSURE TO HIGH-DOSE MUSTARD GAS
  • CONCLUSIONS
  • CANCER IN OTHER ORGANS
  • REFERENCES
  • APPENDIX
  • PRESCRIPTION FOR DYSPNEA EXACERBATION AN
  • PRESCRIPTION FOR DYSPNEA EXACERBATION
  • PRESCRIPTION FOR DYSPNEA EXACERBATION CO
  • Index
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • L
  • M
  • N
  • O
  • P
  • R
  • S
  • T
  • V
  • Back Cover

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