In this long-awaited 2nd edition of a classic book, leading neuroscientists critically review the latest advances made in our understanding of the fundamental molecular, biochemical, behavioral, and pharmacological properties of GABA receptors. The distinguished contributors clarify the approaches being taken to identify and develop new therapeutic agents for such neurological and psychiatric disorders as epilepsy, memory loss, affective illnesses, and psychosis. They also examine the therapeutic potential that remains in the cloning and expression of the GABA transporter, and in developing additional agents capable of regulating GABA receptor function. The book will play a key role in further expanding the list of drugs that interact with the GABA neurotransmitter system.
Rezensionen / Stimmen
This is a very good summary of what is known on GABA receptors today and this is of great interest for neurobiologists, pharmacologists and neurophysiologists-ACTA Nuerologica Belgica
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ISBN-13
978-1-4757-2597-1 (9781475725971)
DOI
10.1007/978-1-4757-2597-1
Schweitzer Klassifikation
1 Structure and Function of GABA Reuptake Systems.- 2 Diversity in Structure, Pharmacology, and Regulation of GABAA Receptors.- 3 GABAA Receptor Agonists, Partial Agonists, and Antagonists.- 4 Pharmacology of Mammalian GABAA Receptors.- 5 The Interaction of Intravenous Anesthetic Agents with Native and Recombinant GABAA Receptors: An Electrophysiological Study.- 6 Electrophysiology of GABAB Receptors.- 7 Pharmacology of Mammalian GABAB Receptors.- 8 Cellular and Biochemical Responses to GABAB Receptor Activation.- 9 Biochemical and Molecular Properties of GABAB Receptors.- 10 Chemistry of GABAB Modulators.- 11 Molecular Biology, Pharmacology, and Physiology of GABAC Receptors.
