This volume provides a comprehensive, state-of-the art review of the field of cell therapy. The volume begins with an overview of the breadth of the field and then turns to overviews of imaging technologies that can aid in both safety and efficacy evaluations. The book then turns to numerous contributions detailing the rapidly growing field of stem cell therapies. These sections cover our understanding of the natural roles of stem cells in biology and human disease and then touches on several of the more prominent areas where stem cells are moving rapidly into clinical evaluation including neurodegenerative diseases, muscular dystrophy, cardiac repair, and diabetes. The volume concludes with contributions from experts in oncology, ophthalmology, stem cells, 3-D printing, and biomaterials where the convergence of expertise is leading to unprecedented insights into how to minutely control the in vivo fate and function of transplanted and/or endogeneously mobilized cells. Finally, the book provides insights into the pivotal relationship between academic and industrial partnerships.
This volume is designed to touch on the major areas where the field will make its greatest and most immediate clinical impacts. This text will provide a useful resource for physicians and researchers interested in the rapidly changing filed of cell therapy.
Dwaine F. Emerich, PhDVP R&DNsGene, inc.225 Chapman StreetProvidence Rhode Island 02905Phone: 401-429-9249
Gorka Orive, PhD
Associate Professor of Pharmacy & Pharmaceutical TechnologyNetworking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBNFaculty of Pharmacy (UPV /EHU)Paseo de la Universidad 701006 Vitoria-Gastez (Spain)Phone: +34 email@example.com
Cell Therapy: Current Status and Future Directions Editors: Dwaine F. Emerich and Gorka Orive Table of Contents Preface - Dwaine F. Emerich and Gorka Orive Chapter 1 - Molecular Considerations in Cell Transplant Imaging - Aline M. Thomas and Jeff W.M. Bulte Chapter 2 - Considerations for Successful Encapsulated ß Cell Therapy - Christopher G. Thanos, Jason L. Gaglia and Felicia W. Pagliuca Chapter 3 - Stem Cell Therapy for Neurovascular and Traumatic Brain Diseases - Marci G. Crowley, M. Grant Liska and Cesar V. Borlongan Chapter 4 - Cell Replacement Strategies for Parkinson's Disease - Diptaman Chatterjee, Dustin R. Wakeman and Jeffrey H. Kordower Chapter 5 - Cell Therapy for Epilepsy - Chiara Falcicchia, Giovanna Paolone and Michele Simonato Chapter 6 - Dendritic Cell-Based Cancer Therapies: Current Status and Future Directions - Shah Md. Shahjahan Miah, Timothy K. Erick and Dwaine F. Emerich Chapter 7 - Encapsulation Approaches to Cell Therapy - Paul de Vos Chapter 8 - Biomaterials and Cells for Re-vascularization - Priscilla A. Williams, Kevin T. Campbell and Eduardo A. Silva Chapter 9 - Cell Reprogramming for Cardiac Regeneration and Rare Disease Modeling - Xonia Carvajal-Vergara, Juan Roberto Rodríguez-Madoz, Beatriz Pelacho and Felipe Prosper< Chapter 10 - Engineering Organoid Systems to Model Health and Disease - James Ankrum, Thomas J. Bartosh, Xiaolei Yin, Alexander Brown, Anthony J. Burand, Jr. and Lauren Boland Chapter 11 - 3D Printing for Cell Therapy Applications - Ashley N. Leberfinger, Kazim Kerim Moncal, Dino J. Ravnic and Ibrahim T. Ozbolat Chapter 12 - Cell Therapy for Ophthalmic Diseases - Konrad Kauper and Arne Nystuen Chapter 13 - Cell Therapy: Approaching a Partnership with Pharma - Vincent Ling Chapter 14 - Stem Cell Therapy in Duchenne Muscular Dystrophy - Mirella Meregalli, Marzia Belicchi and Yvan Torrente