First published in 1988, many chemical compounds present in workplace settings can produce a number of impairments in the human nervous system. As the situations in which neurotoxic agents have been recognized in exposed workers has grown, so has the importance of occupational neurotoxicology as a specialty. Addressing some of the most vital concerns in the field, Occupational Neurotoxicology discusses:
Neurotoxic agents commonly encountered in the workplace
Signs and symptoms of neurotoxicity and of the factors affecting neurotoxic effects
Biological monitoring and the use of biomarkers
Epidemiological methods and clinical approaches to occupational neurotoxicology
The analysis of behavioral, electrophysiological, and imaging techniques in the diagnosis of neurotoxicity
Occupational neurotoxicity in developing countries
The evaluation and management of occupational illnesses due to neurotoxicity
Occupational Neurotoxicology concisely covers important facts on the adverse effects of chemical, biological, and physical agents that can impair or alter the structure of the nervous system. Professionals and researchers in the fields of occupational medicine, toxicology, epidemiology, neurology, industrial hygiene, and psychology will all find relevant information on the health problems that can occur from exposure to neurotoxicants.
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Lucio G. Costa, Ph.D., is a Professor of Toxicology and Director of the Toxicology Program in the Department of Environmental Health at the University of Washington in Seattle. Dr. Costa received his doctoral degree at the University of Milano, Italy, and after post doctoral training at the University of Texas Medical School in Houston, joined the faculty of the University of Washington in 1983. He holds Adjunct Faculty positions at the University of Milano and Pavia, Italy. Dr. Costa is a member of the Society of Toxicology, Society for Neuroscience and the Italian Society of Toxicology and of Pharmacology, and was elected Fellow of the American Association for the Advancement of Science. He is also a Fellow of the Academy of Toxicological Sciences and has served as President of the International Neurotoxicology Association. He received the Achievement Award and the Zeneca Lectureship Award from the Society of Toxicology. Dr. Costa is the author of more than 200 publications in the field of neurotoxicology and has served on several national and international panels and review committees. Luigi Manzo, M.D., is a Professor in the Department of Internal Medicine and Therapeutics and Director of the post-graduate school of Medical Toxicology at the University of Pavia, Italy. He is also involved in graduate and postgraduate training in Toxicology, Occupational Medicine, Hematology, Clinical Neurophysiology, and Psychiatry at the Universities of Pavia and Milan, Italy. Dr. Manzo serves as the Director of the Toxicology Division and the National Toxicology Information Centre at the Salvatore Maugeri Foundation, Pavia Medical Institute. Aside from being the author of more than 100 articles in peer reviewed journals and several book chapters, he has edited 10 books in the areas of toxicology and envirnomental medicine. Dr. Manzo has been the coordinator of international research programs and has served on peer review panels and the editorial boards of several scientific journals. He currently is a member of the Executive Committee of the Italian Society of Toxicology and the coordinator of the Medical Toxicology Section. He is also an active member of the Society of Toxicology (SOT), the Neurotoxicology Specialty Section, and the International Neurotoxicology Association. Dr. Manzo obtained his training at the University of Pavia, receiving the degrees in Medicine and Surgery and in Pharmacy.
Manifestations of Neurotoxicity in Occupational Diseases, L. Manzo and L.G. Costa
Metabolism and Toxicity of Occupational Neurotoxicants: Genetic, Physiological, and Environmental Determinants, S.M. Candura, L. Manzo, A.F. Castoldi, and L.G. Costa
Biological Monitoring of Occupational Neurotoxicants, P. Hoet and R. Lauwerys
Biomarkers in Occupational Neurotoxicology, L.G. Costa and L. Manzo
Epidemiological Methods in Occupational Neurotoxicology, H. Checkoway and M.R. Cullen
Evaluation and Management of Neurotoxicity in Occupational Illness, L. Manzo and V. Cosi
Role of Occupational Neurotoxicants in Psychiatric and Neurodegenerative Disorders, S.M. Candura, L. Manzo, and L.G. Costa
Sensory System Alterations Following Occupational Exposure to Chemicals, D. Fox
Electrophysiological Approaches to Occupational Neurotoxicology, A.M. Seppalainen
Role of Brain Imaging Techniques in Occupational Neurotoxicology, G. Triebig
Computer-Assisted Testing, A. Iregren
Computer Systems in Prevention and Diagnosis of Occupational Neurotoxicology, S. Lloyd, A.H. Hall, and B.H. Rumack
Risk Assessment for Occupational Neurotoxicants, W. Slikker, Jr.
Occupational Neurotoxic Diseases in Developing Countries, F. He
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