It is anticipated that submicron emulsion and lipid suspension will find numerous and novel medical applications in the near future. The purpose of this multi-authore book is to provide the reader with an up-to-date general overview of submicron emulsions and lipid suspensions (solid lipid nanoparticles) as well as to emphasize the various methods of preparation, characerization, evaluation and potential applications in various therapeutic areas.
Leading authors have contributed to this unique book which contains all state of the art and detailed knowledge related to the physico-chemical, pharmaceutical and medical aspects of these most interesting but complex dosage forms, thus making this information easily available to the reader. This book will be of interest to scientists working in the field of drug delivery and targeting in universities as well as in the pharmaceutical, food, cosmetic, veterinary and chemical industries.
Simon Benita is Professor in the School of Pharmacy at the Hebrew University of Jerusalem. Israel. He is the author and co-author of more than 180 professional publications. and holder and coholder of 11 patents. He also serves on the editorial boards of several scientific journals. Professor Benita is a member of the Board of Pharmaceutical Sciences of the International Pharmaceutical Federation, a member of the executive committee of the International Microencapsulation Society, and Governor of the Controlled Release Society. His research interests focus on new microparticulate and nanoparticulate targetable drug delivery systems for parenteral. ocular. and oral administration.
1. Introduction and Overview Part 1. Intravenous Fat Emulsions 2. Perspectives on the Use of Intravenous Lipid Emulsions in Man 3. Particle-Sizing Technologies for Submicron Emulsions 4. Biofate of Fat Emulsions Part 2. Submicron Emulsions as Therapeutic Delivery Systems 5. Design and Evaluation of Submicron Emulsions as Colloidal Drug Carriers for Intravenous Administration 6. Submicron Emulsions as Drug Carriers for Tropical Administration 7. Emulsions of Supercooled Melts - A Novel Drug Delivery System 8. Submicron Lipid Suspensions (Solid Lipid Nanoparticles) Versus Lipid Nanoemulsions: Similarities and Differences 9. Solid Lipid Nanoparticles (SLN) for Controlled Drug Delivery Part 3. Perfluorochemical Submicron Emulsions 10. The Design and Engineering of Oxygen-Delivering Fluorocarbon Emulsions
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