Frontiers in Natural Product Chemistry: Volume 4

 
 
Frontiers in Natural Product Chemistry (Verlag)
  • 1. Auflage
  • |
  • erschienen am 8. Oktober 2018
  • |
  • 287 Seiten
 
E-Book | ePUB mit Adobe DRM | Systemvoraussetzungen
978-1-68108-725-2 (ISBN)
 

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring com

  • Englisch
  • Sharjah
  • |
  • Vereinigte Arabische Emirate
PublishDrive
  • 5,37 MB
978-1-68108-725-2 (9781681087252)
weitere Ausgaben werden ermittelt
  • Intro
  • CONTENTS
  • PREFACE
  • List of Contributors
  • Plant-Based Antiamoebic Natural Products: Literature Review and Recent Developments
  • Neelam Bharti1,*, Prabhu P. Mohapatra2 and Shailendra Singh3
  • INTRODUCTION AND BACKGROUND
  • Search for Herbal Antiamoebic Compounds
  • Standard Extraction Procedure
  • Alkaloids
  • Terpenes and Quassinoids
  • Flavonoids and Iridoids
  • Miscellaneous
  • CONCLUSION AND OUTLOOK
  • DISCLOSURE
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGMENT
  • REFERENCES
  • From Plant to Bench: Natural Products as Source for Analgesic Drug Development
  • Rita Turnaturi1,*, Lorella Pasquinucci1 and Carmela Parenti2
  • INTRODUCTION
  • SALVINORIN A
  • Traditional Use and Botanical Description
  • Analgesic Effect
  • Other Effects
  • Constituents of Salvia Divinorum
  • Salvinorin A Derivatives
  • 1. Structural Derivatization of the C-2 Position.
  • MOPr ligands
  • 2. Structural Modifications of the Tricyclic Trans-Decalin Core
  • Modifications to the C-12 Furan Ring
  • MITRAGYNINE
  • Botanical Description and Traditional Use
  • Analgesic Effect
  • Anti-inflammatory Effects
  • Putative Addictive Properties
  • Constituents of Mitragyna Speciosa
  • Structure-Activity Relationship
  • Structural Derivatization of the C-9 Position
  • Structural Derivatization of the C-7 Position
  • Structural Derivatization of the Nb Lone Pair and ß-Methoxyacrylate mojety
  • Structural Derivatization of the C-19 Position
  • Mitragynine Pseudoindoxyl
  • CONCLUSIONS
  • ABBREVIATIONS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTERESTS
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Essential Oils and Cognitive Performance
  • Snezana Agatonovic-Kustrin1,2 and David W. Morton2,*
  • INTRODUCTION
  • A Brief History of Aromatherapy
  • Aromatherapy with Essential Oils
  • The Pharmacological Hypothesis of Aromatherapy
  • The Psychological Hypothesis
  • The Olfactory Function of Aromatherapy (Smell)
  • Improving Mood and Cognitive Function using Essential Oils
  • The Cholinergic Hypothesis, Essential Oils, and Alzheimer's Disease
  • The Oxidative Stress Hypothesis, Essential Oils, and Alzheimer's Disease
  • CONCLUDING REMARKS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTERESTS
  • ACKNOWLEDGEMENT
  • REFERENCES
  • Inspired by Nature: Modern Medicines Derived from Cannabis
  • Bruno M. Fonseca*, Georgina Correia-da-Silva and Natércia Teixeira
  • 1. CANNABIS, CANNABINOIDS AND THEIR MEDICAL USE
  • 1.1. A Brief History of Cannabis Use in Medicine
  • 1.2. Cannabinoids
  • 2. MECHANISMS OF ACTION OF CANNABINOIDS
  • 2.1. Cannabinoid Receptors
  • 2.2. Cannabinoid Signalling Pathways
  • 2.3. The Endocannabinoid System
  • 3. CANNABIS AS MEDICINE
  • 3.1. Cannabinoid-Based Drugs Metabolism
  • 3.2. Cannabinoid Therapeutic Applications
  • 3.2.1. Antiemetic and Appetite Stimulant
  • 3.2.2. Cannabinoids and Food Intake
  • 3.2.3. Multiple Sclerosis
  • 3.2.4. Chronic Pain
  • 3.2.5. Epilepsy
  • 3.3. Main Limitations of Cannabinoids Use
  • 4. CONCLUDING REMARKS
  • ABBREVIATIONS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGMENT
  • REFERENCES
  • Lectins as Biorecognition Elements in Biosensors for Clinical Applications in Cancer
  • Maria Luísa Soares da Silva1,2,*
  • 1. LECTINS
  • 1.1. Definition, History, Occurrence and Isolation
  • 1.2. Functions and Properties
  • 1.3. Lectin Structures and Classification
  • 2. LECTINS AS TOOLS FOR THE SEPARATION AND STUDY OF GLYCOPROTEINS IN BIOLOGICAL FLUIDS
  • 2.1. Lectin-affinity Chromatography
  • 2.2. Lectin Arrays
  • 2.3. Enzyme-linked Lectin Assay
  • 2.4. Lectin Biosensors
  • 2.4.1. Glycan Biomarkers for Cancer Diagnosis
  • 2.4.2. Lectins as Biorecognition Elements in Biosensors for Cancer Biomarkers
  • 3. CONCLUDING REMARKS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTERESTS
  • ACKNOWLEDGEMENT
  • REFERENCES
  • Brassinosteroids: Occurrence, Structure and Stress Protective Activities
  • Indu Sharma1, Renu Bhardwaj2, Vandana Gautam2, Ravdeep Kaur2 and Ashutosh Sharma3,*
  • INTRODUCTION
  • OCCURRENCE OF BRASSINOSTEROIDS
  • STRUCTURES OF BRASSINOSTEROIDS
  • BIOSYNTHESIS OF BRASSINOSTEROIDS
  • PHYSIOLOGICAL ROLES OF BRASSINOSTEROIDS
  • IMPLICATIONS OF BRASSINOSTEROIDS IN PLANT STRESS MANAGEMENT
  • MECHANISM OF BRASSINOSTEROIDS ACTION
  • INTERACTIONS OF BRASSINOSTEROIDS WITH OTHER PGRS
  • FUTURE OUTLOOK
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTERESTS
  • ACKNOWLEDGEMENT
  • REFERENCES
  • Chemistry and Structures of Plant Derived Antimalarials and Their Semi-synthetic Analogues
  • Samir Mehndiratta1, Mantosh Kumar Satapathy2, Suhani Mankotia3 and Kunal Nepali1,*
  • INTRODUCTION
  • Life Cycle of Malaria [4]
  • 1. Alkaloidal Antimalarials
  • a. Bisbenzylisoquinolines [15 - 17]
  • b. Azaanthracene Alkaloid [13, 17]
  • c. Protoberberine and Aporphine-benzylisoquinoline [13, 18]
  • d. Morphinan Alkaloid [12, 13, 19]
  • e. Naphtylisoquinolines [12, 20]
  • f. Indoloquinoline Alkaloid [12, 21, 22]
  • g. Indole Alkaloids [26, 12, 27]
  • h. Benzofenantridine [12]
  • i. Furoquinoline & Acridone [12, 28]
  • j. Tetrahydroquinoline [12]
  • 2. Antiplasmodial Non-Alkaloidal Natural Products
  • a. Quassinoids [8b, 13, 30]
  • b. Sesquiterpenes [8b, 32]
  • c. Triterpenoids [8b, 13, 35, 36]
  • d. Flavonoids and Xanthones [8b, 13]
  • e. Quinones [8b, 13]
  • Patents on Antimalarial Agents
  • a). Compounds Patented by Keilhauer et al [57].
  • b). Compounds (bisquinolines) Patented by Vennerstrom et al [58].
  • c). Compounds Patented by Raynes et al [59].
  • d). Compound (Spiro and dispiro 1,2,4 trioxolane) Patented by Vennerstrom et al [60].
  • e). Compounds Patented by Sparatore et al [61]
  • f). Compounds Patented by Gilbert et al [62]
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTERESTS
  • ACKNOWLEDGEMENT
  • REFERENCES
  • SUBJECT INDEX

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