
Comprehensive Guide to Nutrition in Polycystic Ovarian Syndrome (PCOS)
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Inhalt
- Intro
- Contents
- List of Tables
- List of Figures
- Preface
- Acknowledgments
- List of Acronyms and Abbreviations
- Part I: The Science behind the Disorder of Polycystic Ovary Syndrome (PCOS)
- Chapter 1
- About Polycystic Ovarian Syndrome
- 1.1. History of Polycystic Ovarian Syndrome
- 1.2. The Female Reproductive System
- 1.2.1. An Introduction to Follicles
- 1.2.2. The First Eighty-Five (85) Days of Follicle Development
- 1.2.3. The Normal Development of Ovarian Follicles during the Menstrual Cycle
- 1.3. Stages of Follicle Development
- 1.3.1. The Hormonal Cascade in Follicle Development
- 1.3.2. Importance of Theca and Granulosa Cells
- 1.4. The Impact of PCOS on the Menstrual Cycle
- 1.5. Clinical Presentation of PCOS
- 1.5.1. Measurable, Clinical Symptoms
- 1.5.2. Subjective, Self-Reported Symptoms
- 1.5.3. Depression, Anxiety, Quality of Life, and Disordered Eating
- 1.6. Definition and Diagnosis of PCOS
- 1.6.1. NIH 1990 Criteria
- 1.6.2. Rotterdam 2003 Criteria
- 1.6.3. AE-PCOS Criteria of 2006 & 2009
- 1.6.4. NIH 2012 Criteria
- 1.7. Prevalence and Health Risks of PCOS
- Chapter 2
- Factors in the Pathophysiology of PCOS
- 2.1. Overview
- 2.2. The Effect of Insulin on PCOS
- 2.3. Effect of Insulin on the HPO-Axis
- 2.4. Insulin Resistance, PCOS and the Metabolic Syndrome
- 2.5. Insulin Resistance, Hyperandrogenism and PCOS
- 2.6. Obesity and Fat Distribution
- 2.7. Abdominal Fat-Cell Dysfunction and PCOS
- 2.7.1. Leptin
- 2.7.2. Adiponectin
- 2.8. Nutrition-Related Factors Relevant to Ovarian Dysfunction
- 2.8.1. Nutrient Excess
- 2.8.1.1. Adipose Tissue
- 2.8.1.2. Reproduction
- 2.8.1.3. Liver
- 2.8.1.4. Pancreas
- 2.8.2. Nutrition-Induced Inflammation
- 2.8.3. Advanced Glycation End-Products (AGEs)
- 2.8.4. Trans Fats
- 2.8.5. Fructose: The Effect of Excessive Fructose Consumption on the Development of Insulin Resistance and Metabolic Syndrome
- 2.8.5.1. Differences in Metabolic Pathways of Glucose and Fructose
- 2.8.5.2. Fructose Contents of Different Sources
- 2.8.6. Fructose: A Highly-Lipogenic Nutrient
- 2.9. The Role of Anti-Müllerian Hormone
- 2.10. Genetic and Androgen Exposure Factors and PCOS
- 2.11. Environmental Factors and PCOS
- 2.11.1. Smoking
- 2.11.2. Drugs, Caffeine and Alcohol
- 2.11.3. Physical Activity
- 2.11.4. Environmental Pollutants
- 2.11.4.1. Organic Solvents
- 2.11.4.2. Aromatic Amines
- 2.11.4.3. Heavy Metals
- 2.11.5. Shift Work
- 2.12. The Role of Appetite Regulation in PCOS
- 2.12.1. Cholecystokinin
- 2.12.2. Ghrelin
- 2.12.3. Leptin
- Chapter 3
- Brief Overview of Drugs and Surgery Used for Treatment in PCOS
- 3.1. Menstrual Irregularities and the Use of Oral Contraceptive Pills
- 3.2. Fertility
- 3.2.1. Anti-Estrogens
- 3.2.2. Insulin Sensitizers
- 3.2.3. Ovarian Drilling
- 3.2.4. Gonadotropins
- 3.2.5. Assisted Reproductive Technology
- 3.2.6. Bariatric Surgery
- Chapter 4
- Alternative and Complementary Treatments for Use in PCOS
- 4.1. Myo-Inositol and D-Chiro-Inositol
- 4.2. Berberine
- 4.3. N-Acetyl Cysteine
- 4.4. Resveratrol
- 4.5. Folic Acid
- 4.5.1. Overview of Folate and Folic Acid
- 4.5.2. Dietary Need for Folic Acid
- 4.5.3. Recommendations
- 4.6. Vitamin D
- 4.7. Adiponectin
- 4.8. Fatty Acids
- 4.8.1. Overview of Fatty Acids
- 4.8.2. Supplementation of Fatty Acids
- Chapter 5
- PCOS in Adolescence
- 5.1. Overview
- 5.2. Investigations and Diagnosis of PCOS in Adolescence
- 5.2.1. Androgen Excess
- 5.2.2. Irregular Menses
- 5.2.3. Ovarian Polycystic Morphology
- 5.3. Obesity, Insulin Resistance and Metabolic Risk
- 5.4. Treatment of PCOS in Adolescence
- Part II: Nutritional Considerations and Treatment Strategies for the Woman with PCOS
- Chapter 6
- The Optimal Diet for PCOS
- 6.1. A Historical Overview
- 6.2. The Nurses' Health Study
- 6.2.1. Nurses' Health Study: Original Cohort
- 6.2.2. Why Nurses?
- 6.2.3. Establishing the Cohort
- 6.3. Dropout
- 6.4. Dietary Entities of Concern to PCOS Nutrition
- 6.4.1. Trans Fat
- 6.4.2. Glycemic Index and Glycemic Load
- 6.4.3. Protein
- 6.4.3.1. Iron in Protein-Rich Foods
- 6.4.3.2. Bioavailability of Non-Heme Sources of Iron
- 6.4.3.3. Benefits of Higher Protein
- 6.4.4. Fructose Excess and AGEs
- 6.4.5. Dairy Products
- 6.4.5.1. Hormones in Milk
- 6.4.5.2. Other Additions to Milk
- 6.4.5.3. Recommendations
- 6.4.6. Gluten
- 6.4.7. Food Cravings
- 6.4.8. Meal Frequency and Snacking
- Chapter 7
- New Dietary Strategies for Treatment in PCOS
- 7.1. Introduction
- 7.2. What Do We Know for Sure?
- 7.3. The Ketogenic and Low Carbohydrate Diet
- 7.4. Intermittent Fasting
- 7.4.1. Methods of Intermittent Fasting as a Lifestyle
- 7.4.2. Combining Ketogenesis with Intermittent Fasting
- 7.5. Overcoming the "Diet" Mentality
- 7.6. A Final Word
- References
- Author's Contact Information
- Index
- Blank Page
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