Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics

A Case-Based Clinical Guide
 
 
Springer (Verlag)
  • erschienen am 11. September 2018
 
  • Buch
  • |
  • Softcover
  • |
  • 364 Seiten
978-3-319-87074-8 (ISBN)
 
This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.
Softcover reprint of the original 1st ed. 2017
  • Englisch
  • Cham
  • |
  • Schweiz
Springer International Publishing
  • Für Beruf und Forschung
  • 142 s/w Abbildungen, 89 farbige Tabellen, 24 farbige Abbildungen
  • |
  • 89 Tables, color; 24 Illustrations, color; 142 Illustrations, black and white; XV, 347 p. 166 illus., 24 illus. in color.
  • Höhe: 235 mm
  • |
  • Breite: 155 mm
  • |
  • Dicke: 19 mm
  • 550 gr
978-3-319-87074-8 (9783319870748)
10.1007/978-3-319-61407-6
weitere Ausgaben werden ermittelt

Emmanuelle Waubant, MD, PhD

Professor of Neurology and Pediatrics

University of California San Francisco

San Francisco, CA, USA

Timothy E. Lotze, MD

Associate Professor of Child Neurology

Department of Pediatrics; Division of Neurology and Developmental Neuroscience

Baylor College of Medicine / Texas Children's Hospital

Houston, TX, USA


SECTION I: Diseases that Affect the Brain.- 1. Acute Disseminated Encephalomyelitis.- 2. Acute Necrotizing Encephalopathy mimicking ADEM.- 3. Pediatric Multiple Sclerosis Manifesting with Primary Psychiatric Symptoms.- 4. Multiple Sclerosis in the Extremely Young.- 5. Breakthrough Disease in Pediatric MS.- 6. Neuromyelitis Optica Spectrum Disorder with Neuropsychiatric Presentation.- 7. Pediatric Tumefactive Demyelination.- 8. Radiologically Isolated Syndrome.- 9. Anti-Glutamic Acid Decarboxylase Limbic Encephalitis.- 10. Anti-NMDA Receptor Antibody Encephalitis.- 11. Pediatric Central Nervous System Vasculitis.- 12. Neuroinflammatory disease in association with Morphea (Localized Scleroderma).- 13. Susac's Syndrome.- 14. Infectious Mimics of Multiple Sclerosis.- 15. Central nervous system lymphoma.- 16. Methotrexate Toxicity.- 17. Alexander Disease Type II.- 18. Neurodegenerative Langerhans Cell Histiocytosis.- 19. X-linked Adrenoleukodystrophy.- 20. Rapid-onset Obesity with Hypothalamic dysfunction, Hypoventilation and Autonomic Dysregulation (ROHHAD).- 21. ADEM Mimic with Thiamine Transporter Deficiency.- SECTION II: Diseases that Affect the Brainstem.- 22. Acute Disseminated Encephalomyelitis-Brainstem and Cerebellar Presentation.- 23. Multiple Sclerosis with Brainstem Presentation.- 24. Neuromyelitis Optica Spectrum Disorder with Brainstem Presentation.- 25. Infection mimics with brainstem presentation.- 26. Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids.- SECTION III: Diseases that Affect the Spinal Cord.- 27. Acute Disseminated Encephalomyelitis with Spinal Cord Presentation.- 28. Post-Infectious Acute Transverse Myelitis.- 29. Complete transverse myelitis (idiopathic).- 30. Transverse Myelitis with Acute Inflammatory Polyradiculoneuropathy.- 31. Acute Flaccid Myelitis.- 32. Neuromyelitis optica spectrum disease with transverse myelitis presentation.- 33. Transverse myelitis in lupus.- 34. Acute Demyelination associated with TNF alpha- inhibiting biologic therapy.- 35. Myelopathy due to occult trauma mimicking transverse myelitis.- 36. Hypomyelination with Brainstem and Spinal Cord Abnormalities and Leg Spasticity (HBSL).- SECTION IV: Diseases That Affect the Optic Nerve.- 37. Acute disseminated encephalomyelitis followed by recurrent or monophasic optic neuritis.- 38. Chronic Relapsing Inflammatory Optic Neuropathy (CRION).- 39. Optic Neuritis as the Presenting Symptom for MS.- 40. Steroid Dependent Recurrent Optic Neuritis in Pediatric Multiple Sclerosis.- 41. Neuromyelitis optica presenting with bilateral optic neuritis.- 42. Sarcoidosis with Optic Nerve Presentation.


This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.

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