Modulation of Presynaptic Calcium Channels

Spatial and temporal regulation of Ca²⁺ channels.- Neuronal functions of auxiliary calcium channel subunits.- Reciprocal regulation of neuronal calcium channels by synaptic proteins.- Molecular architecture of Ca²⁺ channel complexes organized by ß subunits in presynaptic active zones.- Control of Ca_V2 calcium channels and neurosecretion by heterotrimeric G protein coupled receptors.- Regulation of Ca_V2 channels by small GTPases.- Protein interaction partners of Ca_v2.3 R-type voltage-gated calcium channels.- Voltage-gated calcium channel signaling to the nucleus.- Presynaptic Ca²⁺ influx and its modulation at auditory calyceal terminals.- Use of synthetic Ca²⁺ channel peptides to study presynaptic function.- Impact of a loss-of-function P/Q type Ca²⁺ channel mutation on excitatory synaptic control of cerebellar Purkinje neurons.- Ca_V2.1 (P/Q) voltage activated Ca²⁺ channels and synaptic transmission in genetic and autoimmune diseases.- Splicing and editing to customize Ca_V channel structures for optimal neural function.- Presynaptic calcium channels as drug targets for pain.- Sensory pathway modulation by calcium channel a₂d₁ subunit.