"Volume 33 focuses on the vibrant research area of probing nucleic acids--the carriers of the genetic code--by metal ion complexes of small molecules providing an authoritative, timely account of this fascinating topic by over 50 distinguished experts."
Rezensionen / Stimmen
". . .draws on the experience of recognized international experts to review the present status of research in this area. . . . . .a very useful volume, complementing Volume 32. . .recommended to all those with an interest in this area of bioinorganic chemistry. "
---Platinum Metals Review
Reihe
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Maße
Höhe: 280 mm
Breite: 210 mm
Gewicht
ISBN-13
978-0-8247-9688-4 (9780824796884)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Klassifikation
Herausgeber*in
University of Basel, Switzerland
University of Basel, Switzerland
Molecular modelling of transition metal adducts with nucleic acids and their constituents; zinc complexes as targeting agents for nucleic acids; metallocene interactions with DNA and DNA processing enzymes; evidences for a catalytic activity of the DNA double helix in the reactions between DNA, platinum (II) and intercalators; trans-diammineplatinum (II) - what makes it different from CIS-DDP? coordination chemistry of a neglected relative of cisplatin and its interaction with nucleic acids; metal ions in multiple-stranded DNA; DNA interactions with substitution-intert transition metal ion complexes; effect of metal ions on the fluorescence of dyes bound to DNA; photolytic covalent binding of metal complexes to DNA; electrochemically activated nucleic acid oxidation; electron transfer between metal complexes bound to DNA - is DNA a wire?; porphyrin and metalloporphyrin interactions with DNA; selective DNA cleavage by metalloporphyrin derivatives; synthetic metalloporphyrins as probes of protein-DNA interactions; targeting of nucleic acids by iron complexes; nucleic acid chemistry of the cuprous complexes of 1,10-phenanthroline and derivatives; specific DNA cleavage by manganese (III) complexes; nickel complexes as probes of guanine sites in nucleic acid folding; hydrolytic cleavage of RNA catalyzed by metal ion complexes; RNA recognition and cleavage by iron (III)-bleomycin; metallobleomycin-DNA interactions - structures and reactions related to bleomycin-induced DNA damage.