Stroke Genetics

 
 
Springer (Verlag)
  • 2. Auflage
  • |
  • erschienen am 12. August 2018
 
  • Buch
  • |
  • Softcover
  • |
  • XII, 431 Seiten
978-3-319-85854-8 (ISBN)
 
This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.

Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

Softcover reprint of the original 2nd ed. 2017
  • Englisch
  • Cham
  • |
  • Schweiz
Springer International Publishing
  • Für Beruf und Forschung
  • Überarbeitete Ausgabe
  • 26
  • |
  • 20 s/w Tabellen, 13 s/w Abbildungen, 26 farbige Abbildungen
  • |
  • 20 Tables, black and white; 26 Illustrations, color; 13 Illustrations, black and white; XII, 431 p. 39 illus., 26 illus. in color.
  • Höhe: 23.5 cm
  • |
  • Breite: 15.5 cm
  • 908 gr
978-3-319-85854-8 (9783319858548)
10.1007/978-3-319-56210-0
weitere Ausgaben werden ermittelt

Pankaj Sharma, MD, PhD, FRCP

Reader & Consultant Neurologist

Imperial College London & Hammersmith Hospitals

London, UK

James F. Meschia, MD

Chair, Department of Neurology

Mayo Clinic

Jacksonville, Florida, USA

Introduction.- Familial stroke epidemiology.- Association study results.- GWAS.- Aneurysms/carvernous/AVM.- ICH/amyloid/microbleeds.- CADASIL.- Fabry.- MELAS.- Sickle.- Other monogenic.- White matter disease.- Carotid atherosclerosis.- Dissection.- Pharmacogenomics.- Non-Caucasian stroke genetics.- Small vessel disease.- Genetics of neuroimaging in stroke.- Cerebrovenous thrombosis.- Ethics.

This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.

Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

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