This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair.
Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged.
The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Maskai Ieda is Associate Professor, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
Wolfram H. Zimmermann is Professor and Director of the Institute of Pharmacology, Heart Research Center Georg-August University Göttingen, Germany.
Imaging of Cell Grafts Past and Future of Cell based Heart Repair.- Progenitor Cells from the Adult Heart.- Epicardial Progenitors in the Embryonic and Adult Heart.- Cardiomyocyte Generation from human Pluripotent Stem Cells.- Derivation of Stroma Cells from human Pluripotent Stem Cells.- Direct Cardiac Programming.- Manufacturing of Therapeutic Cells.- Cardiac purification from iPSC-derived cell.- State-of-the-Art in Cardiomyocyte Transplantation.- State-of-the-Art in Tissue Engineering for Heart Repair.- Imaging of Cell Grafts.- Transplant Immunology.able.