Antimicrobial Nanomaterials: Principles and Applications introduces the reader to the microbial world, antimicrobial nanomaterials, how microbial evolution works, and how knowledge of these areas can facilitate the development of sustainable antimicrobials.
Due to the widespread occurrence of multidrug-resistant microbes, there is an increasing interest in the use of novel nanostructured materials as antimicrobials. This book is designed to help researchers from fields such as materials science, nanoscience, and nanoengineering who are attempting to develop these antimicrobial materials.
- Provides crucial background in microbiology and microbial evolution to help researchers design experiments that can produce sustainable results
- Offers detailed coverage on the antimicrobial properties of different types of nanomaterials
- Discusses the major challenges of using nanomaterials for antimicrobial applications
Joseph L. Graves, Jr. is a professor of biological sciences in the Department of Biology, North Carolina A&T State University, Greensboro, North Carolina, USA. His research focuses on the evolutionary genomics of adaptation, particularly as relevant to postponed aging and bacterial responses to nanomaterials.
Section One: Nano and Microbes, A Brief History 1. The Nanoscale: Definitions 2. Characteristics of nanomaterials: Composition, coating, size, shape, surface properties, physical properties (inorganic, polymeric) 3. Manufacture of nanomaterials - environmental exposure, toxicity, green synthesis, and sustainability 4. Natural nanomaterials - microbial exposure 5. MDR microbes and the "magic bullet." - metallic, metallic oxides - NPs
Section Two: Microbial Diversity 6. Three Domains of Life - Structure and Function (Bacteria, Archaea, Eucarya) 7. Bacteriophages and Viruses (not alive, but important) 8. Microbial view of the periodic table 9. Microbial defense
Section Three: Microbes and Why they Matter 10. Food - Spoilage, Preservation, Industrial Microbiology 11. Environment - Biogeochemical Cycles, Pollution 12. Microbiomes - Naturally occurring and engineered 13. Disease - Infectious (acute/chronic) 14. Pharmaceuticals/Biotechnology - engineered proteins, vaccines, DNA vaccines
Section Four: Microbial Evolution 15. Organic Evolution: Principles 16. What Darwin Never Saw: How things differ between the microbial and macroscopic world. (Horizontal gene transfer, co-selection, persister cells) 17. Classic studies of microbial evolution (antibiotic, metal) 18. Evolution and nanomaterials (silver, copper, iron, gallium) 19. Conclusion: Towards Sustainable Antimicrobial Nanomaterials
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