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Praise for the Series:"This serial... is well known to virologists. It is a valuable aid in maintaining an overview of various facets of the rapidly expanding fields of virology... Timely, informative, and useful to student, teacher, and research scientist."--American Scientist"A mandatory purchase for all types of comprehensive libraries, both public and university, as well as for those interested in or doing research in the field of virology."--Military MedicineKey Features* Among the topics covered are:* Virus-induced immunopathology* Filoviruses* Molecular characterization of pestiviruses* Transactivation of cellular genes by hepatitus B virus proteins* Principles of molecular organization, expression, and evolution of closteroviruses* Primate T lymphotropic oncoretroviruses* Replication of positive-stranded RNA viruses of plants and animals
- Front Cover
- Advances in Virus Research, Volume 47
- Copyright Page
- Contents
- Chapter 1. Marburg and Ebola Viruses
- I. Introduction
- II. Epidemiology of Filoviruses
- III. Biology of Filoviruses
- IV. Clinical Virology
- V. Pathology and Immunology
- Note
- References
- Chapter 2. Molecular Characterization of Pestiviruses
- I. Introduction
- II. Pestiviruses: Diseases, Genomes, and Proteins
- III. RNA Recombination: The Molecular Basis for Cytopathogenicity of Pestiviruses
- IV. Large-Scale Jumps Instead of Tiny Steps: Considerations about Viral Evolution
- References
- Chapter 3. Principles of Molecular Organization, Expression, and Evolution of Closteroviruses: Over the Barriers
- I. Introduction
- II. Draft of Closterovirus Taxonomy
- III. Biological Patterns and Cytopathic Effects
- IV. Particle Structure: Closterovirus Are Rattlesnakes, Not Just Threads
- V. Genome Organization and Functions of Gene Products in Closteroviruses
- VI. Expression Strategy
- VII. Evolution of Closteroviruses Genomes
- VIII. Conclusions
- References
- Chapter 4. Comparison of the Replication of Positive-Stranded RNA Viruses of Plants and Animals
- I. Introduction
- II. Virus-Encoded Replication Proteins
- III. Host Proteins in RNA Replication
- IV. The Role of Memhranes in RNA Replication
- V. Cis-Acting Nucleotide Sequences Required for RNA Replication
- VI. Control of Asymnictric Positivc- and Negative-Strand Synthesis
- VII. Concluding Remarks
- References
- Chapter 5. Trans-Activation of Cellular Genes by Hepatitis B Virus Proteins: A Possible Mechanism of Hepatocarcinogenesis
- I. Introduction
- II. The Hepatitis B Virus
- III. Hepatocellular Carcinoma
- IV. HBV Trans-Activators in Hepatocarcinogenesis
- V. Future Research Directions and Clinical Perspectives
- References
- Chapter 6. Autonomous Parvovirus and Densovirus Gene Vectors
- I. Introduction
- II. Parvoviruses
- III. Parvovirus Gene Vectors
- IV. Summary and Prospects
- References
- Chapter 7. Virus-Induced Immunopathology
- I. Introduction
- II. Immunopathological Lesions Which Primarily Involve CD8+ T Cells
- III. Immunopathological Reactions Primarily Involving CD4+ T Lymphocytes
- IV. Immune Inflammatory Responses Involving Antibody
- V. Viruses and Autoimmunity
- VI. Control of Virus-Induced Immune Inflammatory Disease
- VII. Conclusions
- References
- Chapter 8. Geographic and Molecular Epidemiology of Primate T Lymphotropic Retroviruses: HTLV-I, HTLV-II, STLV-I, STLV-PP, and PTLV-L
- I. Introduction and Historical Background
- II. Epidemiological Characteristics of the Different PTLVs
- III. Genetic Structure of HTLV-I/II
- IV. Methods Used in Molecular Epidemiology of PTLVs
- V. HTLV-I
- VI. STLV-I: Close Phylogenetic Relationship with HTLV-I
- VII. HTLV-II
- VIII. STLV-PP and PTLV-L
- IX. Conclusions and Perspective: HTLV-I/II as Privileged Markers of Migration of Ancient Human Populations
- References
- Index
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