Written by experts worldwide, this book provides the current knowledge of growth factors and their receptors in cancer metastasis. It covers basic cellular and molecular biology of growth factors and their receptors, as well as their role in cancer and cancer metastasis in clinical settings. The book is intended for cancer biologists, cell biologists, biochemists, geneticists, oncologists, surgeons and physicians. It is also a valuable reference for those who work in the area of cancer research, cancer therapies, cancer care, pharmaceutical industry. Postgraduates and undergraduates who pursue a research career in cancer and growth factors will find it an extremely useful reference book.
Contributors. The Role of Leukemia Inhibitory Factor in Cancer and Cancer Metastasis; F. Ravandi, Z. Estrov. Interleukin-2 and Its Receptors in Human Solid Tumours: Immunobiology and Clinical Significance; T.L. Whiteside, et al. Interleukin-8 and Angiogenesis; T.A. Martin. The Role of Interleukin-11 in the Formation of Bone Metastases; N. Fujita, T. Tsuruo. Therapeutic Potential of Adenovirus Mediated Interleukin-12 Gene Therapy for Prostate Cancer; S. Ebara, et al. Fibroblast Growth Factors and Their Receptors in Metastases of Prostate and Other Urological Cancers; Z. Culig, et al. Insulin-Like Growth Factor Axis Elements in Breast Cancer Progression; E. Mira, et al. The Role of Platelet Derived Growth Factor (PDGF) and Its Receptors in Cancer and Metastasis; S.W. Feigelson, et al. TGFbeta receptor Signaling in Cancer and Metastasis; M. Oft. VEGF-C/VEGFRS and Cancer Metastasis; Y. Yonemura, et al. HGF-c met receptor Pathway in Tumor Invasion-Metastasis and Potential Cancer Treatment with NK4; K. Matsumoto, T. Nakamura. Growth Factor Receptors and Cell Adhesion Complexes in Cytoskeletal Assembly/Anchorage; G. Davies, et al. Index.