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Lax, Alistair J.

Toxin

The Cunning of Bacterial Poisons

Autor: Lax, Alistair J.
Verlag: Oxford University Press, UK, Oxford
Zusatzinfo: 201 Seiten.
ISBN13: 9780191513909
ISBN10: 0191513903
Erschienen: 27.10.2005
Medientyp: E-Book
Einbandart: ebook
Land: Großbritannien
Sprache: Englisch
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Alistair Lax takes a fascinating look at these most devious molecules, explaining the many ingenious mechanisms they use to penetrate our cell's defences, and the deadly pandemics that result. A story not only of disease but also of human rivalry and persistence in our struggle to understand, combat, and harness these powerful toxins. - ;What do the following have in common: the promise of Botox as the key to everlasting youthful looks; E. coli O157 hamburger disease; a mysterious illness which killed 35 heroin users in 2000; and the assassination by poisoned umbrella-tip of a Bulgarian dissident in the 1970s? The answer is that all of these are caused by toxins, the powerful biological poisons released by bacteria and some plants. In Toxin, Alistair Lax reveals the panoply of ways in which bacterial toxins overcome the defences of our cells. He explains how they work, how they are so successful in causing major diseases, the terrible human impact they have had, and how apparently 'new' diseases arise from them. He also discusses how we can combat toxins, and how we can harness their actions for beneficial purposes. Enlivened by the very human story of the persistence, rivalries, and insights from which modernmicrobiology grew, Toxin is the first widely accessible account of this exciting and important topic. - ;An enjoyable read. I would thoroughly recommend Toxin to students of biology and related subjects. - Susan Omar, Biologist
  • Contents
  • Figures and Tables
  • 1. Toxins are everywhere: how toxins have affected history
  • 2. The germ of an idea: a gradual acceleration up to the mid-1850s
  • 3. The golden age of microbiology: Pasteur, Koch, and the birth of the toxin concept
  • 4. The anatomy of diphtheria: taming the deadly scourge of childhood
  • 5. Understanding: all toxins fit into three basic mechanisms
  • 6. Why are plague and typhoid so deadly?: A further layer of cunning
  • 7. Deviant biology: weapons, espionage, and man's innate inhumanity
  • 8. A more optimistic outcome: from poison to cure and the cell biologist's toolkit
  • 9. Where is toxinology going now?: Is there anything new out there?
  • Endnotes
  • Bibliography
  • Further reading
  • Index
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • Y
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